Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATF1 | P18846 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6840377 | 0.93 | MAPK1 (0.32) | MAPK1ATF1NFKB1 | |
| SCHEMBL1288387 | 0.86 | PIN1 (0.35) | — | |
| SCHEMBL1288351 | 0.79 | PIN1 (0.35) | — | |
| SCHEMBL1288350 | 0.79 | PIN1 (0.35) | — | |
| SCHEMBL31487450 | 0.66 | NFKB1 (0.31) | ATF1NFKB1 | |
| SCHEMBL3667697 | 0.65 | STK17B (0.35) | — | |
| SCHEMBL1288224 | 0.64 | CNR2 (0.35) | — | |
| SCHEMBL1288223 | 0.64 | CNR2 (0.35) | — | |
| SCHEMBL6910148 | 0.64 | HCAR3 (0.32) | — | |
| SCHEMBL27894803 | 0.63 | PIN1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011079114-A1 | PTERIDINONES AS INHIBITORS OF POLO - LIKE KINASE | ELAN PHARMACEUTICALS, INC. (US) | 2011-06-30 | — | — | WO | disclosed |