SCHEMBL6910563

SCHEMBL6910563

C=CC1Cc2ccccc21.C=CCC=CC

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PRCP P42785 1/20 0.44
OPRM1 P35372 1/20 0.40
SIGMAR1 Q99720 3/20 0.40
HTR2A P28223 10/20 0.38
HRH1 P35367 7/20 0.37
HTR2C P28335 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30681591 0.84 PRCP (0.47) PRCPOPRM1SIGMAR1HTR2A
SCHEMBL50587 0.84 PRCP (0.47) PRCPOPRM1SIGMAR1HTR2A
Tetrafluoroethylene SCHEMBL6451837 0.76 PRCP (0.41) PRCPOPRM1SIGMAR1
Styrene SCHEMBL28135034 0.75 ALDH1A1 (0.50) PRCPOPRM1SIGMAR1
SCHEMBL29483960 0.73 OPRM1 (0.41) PRCPOPRM1SIGMAR1HTR2AHTR2C
SCHEMBL22508 0.67
SCHEMBL1760721 0.67
SCHEMBL22509 0.67
SCHEMBL31054997 0.67 PRCP (0.39) PRCPOPRM1SIGMAR1
SCHEMBL1567129 0.66 HTR1A (0.47) PRCPSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6737484-B2 A MOLECULAR WEIGHT DISTRIBUTION, MW/MN, DEFINED BY THE EQUATION: MW/MN LESS-DOUBLE-EQUALS (I10/I2)-4.63, AND A CRITICAL SHEAR STRESS AT ONSET OF GROSS MELT FRACTURE OF GREATER THAN ABOUT 4 X 106 DYNE/CM2 AND THEIR METHOD OF DOW GLOBAL TECHNOLOGIES INC. 2004-05-18 US disclosed
US-20030120004-A1 Elastic substantially linear olefin polymers LAI SHIH-YAW (US) 2003-06-26 US disclosed
US-6548611-B2 Using coordination catalyst DOW GLOBAL TECHNOLOGIES INC. 2003-04-15 US disclosed
US-20010041776-A1 Elastic substantially linear olefin polymers DOW GLOBAL TECHNOLOGIES INC. 2001-11-15 US disclosed