SCHEMBL6911280

SCHEMBL6911280

O=C(/C=C/c1ccccc1)Oc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.57
MEN1 O00255 2/20 0.57
CYP1B1 Q16678 1/20 0.56
ALOX5 P09917 2/20 0.54
MAPT P10636 3/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
RAB9A P51151 2/20 0.53
HPGD P15428 1/20 0.53
PTBP1 P26599 1/20 0.53
MAOB P27338 2/20 0.52
BCHE P06276 1/20 0.52
NFE2L2 Q16236 1/20 0.51
ALDH1A1 P00352 2/20 0.46
HSP90AA1 P07900 1/20 0.46
CCR6 P51684 1/20 0.46
NPC1 O15118 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6911282 1.00 KMT2A (0.57) KMT2AMEN1CYP1B1ALOX5MAPT
SCHEMBL6908275 0.88 CYP1B1 (0.64) KMT2AMEN1CYP1B1MAPTSMN1; SMN2
SCHEMBL7922516 0.88 CYP1B1 (0.64) KMT2AMEN1CYP1B1MAPTSMN1; SMN2
SCHEMBL10744603 0.85 KMT2A (0.64) KMT2AMEN1CYP1B1MAPTSMN1; SMN2
SCHEMBL10744598 0.85 KMT2A (0.64) KMT2AMEN1CYP1B1MAPTSMN1; SMN2
SCHEMBL11432402 0.85 MAOB (0.64) KMT2AMEN1CYP1B1MAPTSMN1; SMN2
SCHEMBL6915908 0.85 MAOB (0.64) KMT2AMEN1CYP1B1MAPTSMN1; SMN2
SCHEMBL13978652 0.84 KMT2A (0.69) KMT2AMEN1CYP1B1MAPTSMN1; SMN2
SCHEMBL5317940 0.82 LMNA (0.65) KMT2AMEN1CYP1B1MAPTSMN1; SMN2
SCHEMBL5317936 0.82 LMNA (0.65) KMT2AMEN1CYP1B1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9122103-B2 Liquid-crystal display device, process for producing liquid-crystal display device, and composition for forming alignment film SHARP KABUSHIKI KAISHA (JP) 2015-09-01 US disclosed
US-9122103-B2 Liquid-crystal display device, process for producing liquid-crystal display device, and composition for forming alignment film SHARP KABUSHIKI KAISHA (JP) 2015-09-01 US disclosed
US-20120314166-A1 LIQUID-CRYSTAL DISPLAY DEVICE, PROCESS FOR PRODUCING LIQUID-CRYSTAL DISPLAY DEVICE, AND COMPOSITION FOR FORMING ALIGNMENT FILM SHARP KABUSHIKI KAISHA (JP) 2012-12-13 US disclosed
US-20120314166-A1 LIQUID-CRYSTAL DISPLAY DEVICE, PROCESS FOR PRODUCING LIQUID-CRYSTAL DISPLAY DEVICE, AND COMPOSITION FOR FORMING ALIGNMENT FILM SHARP KABUSHIKI KAISHA (JP) 2012-12-13 US disclosed
US-6689899-B2 HYDROGENATION OF THE CORRESPONDING DINITRO COMPOUNDS KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2004-02-10 US disclosed
US-20020019558-A1 Diamine and acid anhydride KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019558-A1 Diamine and acid anhydride CA1, ASIC1, CA4 KMT2A 679/4885MEN1 1404/4885CYP1B1 3512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.