Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2352608 | 0.90 | TSHR (0.60) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL2354642 | 0.89 | TSHR (0.61) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL11517249 | 0.86 | TSHR (0.60) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL21771816 | 0.85 | TSHR (0.54) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL21771825 | 0.84 | TSHR (0.55) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL235587 | 0.82 | ALDH1A1 (0.73) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL21143374 | 0.82 | TSHR (0.55) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL6911577 | 0.81 | TSHR (0.75) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL204881 | 0.80 | TSHR (0.61) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 | |
| SCHEMBL28690053 | 0.78 | TSHR (0.59) | TSHRALDH1A1TDP1L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0896969-B1 | Process for preparing solid titanium catalyst component, olefin polymerization catalyst, and olefin polymerization process | MITSUI CHEMICALS INC (JP) | 2004-03-03 | — | — | EP | disclosed |
| EP-0896969-A1 | Process for preparing solid titanium catalyst component, olefin polymerization catalyst, and olefin polymerization process | Mitsui Chemicals, Inc. (JP) | 1999-02-17 | — | — | EP | disclosed |