SCHEMBL6911577

SCHEMBL6911577

CCOC(=O)c1ccccc1C(=O)OCC(C)(C)C

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.75
ALDH1A1 P00352 5/20 0.59
HSD17B10 Q99714 3/20 0.59
CDC25B P30305 2/20 0.54
TDP1 Q9NUW8 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
CYP3A4 P08684 2/20 0.50
TP53 P04637 1/20 0.50
MAPK1 P28482 1/20 0.50
LMNA P02545 2/20 0.49
KDM4E B2RXH2 3/20 0.48
KMT2A Q03164 2/20 0.47
CDC25A P30304 1/20 0.47
CDC25C P30307 1/20 0.47
MEN1 O00255 1/20 0.47
USP2 O75604 1/20 0.47
CYP1A2 P05177 1/20 0.47
MAPT P10636 1/20 0.47
CYP2C9 P11712 1/20 0.47
ALOX15 P16050 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL204881 0.93 TSHR (0.61) TSHRALDH1A1HSD17B10TDP1L3MBTL1
Diethyl Phthalate SCHEMBL29404255 0.87 TSHR (1.00) TSHRALDH1A1HSD17B10CDC25BTDP1
Diethyl Phthalate SCHEMBL22296 0.87 TSHR (1.00) TSHRALDH1A1HSD17B10CDC25BTDP1
Diethyl Phthalate SCHEMBL5306972 0.87 TSHR (1.00) TSHRALDH1A1HSD17B10CDC25BTDP1
SCHEMBL7633775 0.86 ALDH1A1 (0.59) TSHRALDH1A1HSD17B10TDP1L3MBTL1
Diethyl Phthalate SCHEMBL18187693 0.85 TSHR (0.81) TSHRALDH1A1HSD17B10CDC25BTDP1
Diethyl Phthalate SCHEMBL19252611 0.85 TSHR (0.95) TSHRALDH1A1HSD17B10CDC25BTDP1
Diethyl Phthalate SCHEMBL7520316 0.85 TSHR (0.95) TSHRALDH1A1HSD17B10CDC25BTDP1
Diethyl Phthalate SCHEMBL30925693 0.85 TSHR (0.95) TSHRALDH1A1HSD17B10CDC25BTDP1
Diethyl Phthalate SCHEMBL8577506 0.85 TSHR (0.95) TSHRALDH1A1HSD17B10CDC25BTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218087-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN, CATALYST FOR POLYMERIZATION OF OLEFIN, METHOD FOR PRODUCING POLYMER OF OLEFIN, POLYMER OF OLEFIN, METHOD FOR PRODUCING PROPYLENE-BASED BLOCK COPOLYMER, AND PROPYLENE-BASED BLOCK COPOLYMER TOHO TITANIUM CO., LTD. (JP) 2024-07-04 US disclosed
EP-4349874-A1 OLEFIN POLYMERIZATION SOLID CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, MANUFACTURING METHOD FOR OLEFIN POLYMER, OLEFIN POLYMER, MANUFACTURING METHOD FOR PROPYLENE-BASED BLOCK COPOLYMER, AND PROPYLENE-BASED BLOCK COPOLYMER TOHO TITANIUM CO., LTD. (JP) 2024-04-10 EP disclosed
CN-115867395-A Method for producing Mg-containing particles 东邦钛株式会社 2023-03-28 CN disclosed
US-6770586-B2 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD. (JP) 2004-08-03 US disclosed
US-20030130109-A1 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD (JP) 2003-07-10 US disclosed
EP-1209172-A1 SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION Toho Titanium Co., Ltd. (JP) 2002-05-29 EP disclosed