SCHEMBL204881

SCHEMBL204881

CC(C)(C)COC(=O)c1ccccc1C(=O)OCC(C)(C)C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.61
ALDH1A1 P00352 6/20 0.57
TDP1 Q9NUW8 2/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
CYP3A4 P08684 3/20 0.52
MAPK1 P28482 2/20 0.52
TP53 P04637 1/20 0.52
NPC1 O15118 1/20 0.50
LMNA P02545 1/20 0.50
HSD17B10 Q99714 1/20 0.47
HIF1A Q16665 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
GABRP O00591 1/20 0.44
GABRD O14764 1/20 0.44
GABRA1 P14867 1/20 0.44
GABRB1 P18505 1/20 0.44
GABRG2 P18507 1/20 0.44
GABRB3 P28472 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6911577 0.93 TSHR (0.75) TSHRALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL7633775 0.93 ALDH1A1 (0.59) TSHRALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL4625710 0.91 TSHR (0.52) TSHRALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL10396914 0.89 ALDH1A1 (0.56) TSHRALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL5710092 0.89 TDP1 (0.61) TSHRALDH1A1TDP1L3MBTL1NPC1
Ethylene Glycol SCHEMBL23581096 0.88 ALDH1A1 (0.54) TSHRALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL10389101 0.87 ALDH1A1 (0.67) TSHRALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL196719 0.87 ADRB2 (0.56) TSHRALDH1A1L3MBTL1NPC1LMNA
SCHEMBL7062431 0.87 TSHR (0.78) TSHRALDH1A1TDP1L3MBTL1CYP3A4
SCHEMBL28690053 0.86 TSHR (0.59) TSHRALDH1A1TDP1L3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 600 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115926331-B Polybutene-1 alloy and preparation method thereof 中国石油天然气股份有限公司 2025-02-11 CN claimed
EP-3517555-B1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2024-11-27 EP claimed
CN-115894751-B 1-butene polymerization catalyst and preparation method and application thereof 北京石油化工工程有限公司 2024-03-01 CN claimed
EP-3517553-B1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2023-11-08 EP claimed
US-11773192-B2 Process of preparing polyolefin with the discontinuous addition of a thermal runaway reducing agent SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2023-10-03 US claimed
EP-3510056-B2 PROCESS OF PREPARING POLYOLEFIN WITH THE DISCONTINUOUS ADDITION OF A THERMAL RUNAWAY REDUCING AGENT SABIC GLOBAL TECHNOLOGIES BV (NL) 2023-07-19 EP claimed
CN-116199995-A High-fluidity polypropylene resin composition and molded article made from the same 韩华道达尔能源有限公司 2023-06-02 CN claimed
EP-4186931-A1 POLYPROPYLENE RESIN COMPOSITION WITH HIGH FLOWABILITY AND ARTICLE MOLDED THEREFROM Hanwha TotalEnergies Petrochemical Co., Ltd. (KR) 2023-05-31 EP claimed
CN-115926331-A Polybutene-1 alloy and preparation method thereof 中国石油天然气股份有限公司 2023-04-07 CN claimed
CN-115894751-A 1-butene polymerization catalyst and preparation method and application thereof 北京石油化工工程有限公司 2023-04-04 CN claimed
US-10208145-B2 Catalyst component for olefin polymerization, and catalyst containing the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-02-19 US claimed
US-10184017-B2 Catalyst component for propene polymerization, preparation method thereof, and catalyst containing the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-01-22 US claimed
US-20170073441-A1 Catalyst Component For Olefin Polymerization, and Catalyst Containing the Same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2017-03-16 US claimed
EP-3135697-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST THEREOF China Petroleum & Chemical Corporation (CN) 2017-03-01 EP claimed
EP-3135699-A1 CATALYST COMPONENT FOR PROPYLENE POLYMERIZATION, PREPARATION METHOD THEREFOR AND CATALYST HAVING SAME China Petroleum & Chemical Corporation (CN) 2017-03-01 EP claimed
US-20170044280-A1 Catalyst Component for Propene Polymerization, Preparation Method Thereof, and Catalyst Containing the Same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2017-02-16 US claimed
WO-2011158102-A1 CONTINUOUS PROCESS FOR THE PRODUCTION OF POLYESTER RESINS SUITABLE AS BINDERS FOR COMPATIBLE THERMOSETTING PAINTS ANS PAINTS BASED ON SAID POLYESTER RESINS ALCEA - AZIENDA LOMBARDA COLORI E AFFINI S.R.L. (IT) 2011-12-22 WO claimed
US-6770586-B2 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD. (JP) 2004-08-03 US claimed
US-20030130109-A1 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD (JP) 2003-07-10 US claimed
EP-1209172-A1 SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION Toho Titanium Co., Ltd. (JP) 2002-05-29 EP claimed