Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6903462 | 0.81 | POLB (0.30) | — | |
| Hydrochloric Acid SCHEMBL7938933 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL27502080 | 0.74 | GPR3 (0.31) | — | |
| Hydrochloric Acid SCHEMBL7716982 | 0.73 | GPR3 (0.39) | — | |
| Hydrochloric Acid SCHEMBL8361501 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL6904899 | 0.73 | BCHE (0.31) | — | |
| SCHEMBL27521611 | 0.73 | GPR3 (0.33) | — | |
| SCHEMBL7895917 | 0.72 | GPR3 (0.32) | — | |
| SCHEMBL7941677 | 0.70 | HTR2A (0.39) | — | |
| Hydrochloric Acid SCHEMBL2114856 | 0.69 | DHFR (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991677-B1 | PROCESS FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE WITH ALPHA-OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2004-06-16 | — | — | EP | disclosed |
| US-20020156209-A1 | Polymerization in the presence of metallocene catalysts with bridged bis-indenyl compounds | BASELL TECHNOLOGY COMANY BV (NL) | 2002-10-24 | — | — | US | disclosed |
| US-6448350-B1 | Process for the preparation of copolymers of ethylene with alpha-olefins | BASELL TECHNOLOGY COMPANY BV (NL) | 2002-09-10 | — | — | US | disclosed |
| US-6268518-B1 | AS POLYMERIZATION CATALYSTS FOR POLYMERIZATION OF OLEFINS | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 2001-07-31 | — | — | US | disclosed |
| EP-0991677-A1 | PROCESS FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE WITH ALPHA-OLEFINS | Montell Technology Company bv (NL) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999054369-A1 | PROCESS FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE WITH ALPHA-OLEFINS | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 1999-10-28 | — | — | WO | disclosed |
| EP-0914323-A1 | METALLOCENES AND CATALYSTS FOR POLYMERIZATION OF OLEFINS | Montell Technology Company B.V. (NL) | 1999-05-12 | — | — | EP | disclosed |
| WO-1998043989-A1 | METALLOCENES AND CATALYSTS FOR POLYMERIZATION OF OLEFINS | MONTELL TECHNOLOGY COMPANY B.V. (NL) | 1998-10-08 | — | — | WO | disclosed |