SCHEMBL6911488

SCHEMBL6911488

Nc1cccc(C(=O)N(CC=CC(=O)O)c2ccccc2)c1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.47
MEN1 O00255 4/20 0.47
PBRM1 Q86U86 1/20 0.45
POLB P06746 3/20 0.43
ADRA2C P18825 1/20 0.43
TSHR P16473 2/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ALDH1A1 P00352 4/20 0.40
HTT P42858 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HDAC1 Q13547 1/20 0.36
GAA P10253 2/20 0.36
RAB9A P51151 1/20 0.35
NPC1 O15118 1/20 0.35
MITF O75030 1/20 0.35
LMNA P02545 1/20 0.35
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7927019 0.85 MEN1 (0.48) KMT2AMEN1POLBADRA2CTSHR
SCHEMBL6909361 0.85 MEN1 (0.47) KMT2AMEN1POLBADRA2CTSHR
SCHEMBL6909358 0.78 KMT2A (0.48) KMT2AMEN1POLBADRA2CTSHR
SCHEMBL6908305 0.77 KDM4E (0.47) KMT2AMEN1POLBADRA2CTSHR
SCHEMBL6323267 0.75 ALDH1A1 (0.59) KMT2AMEN1PBRM1POLBADRA2C
SCHEMBL6909155 0.72 TSHR (0.45) KMT2AMEN1TSHRALDH1A1RAB9A
SCHEMBL2129928 0.72 PBRM1 (0.58) KMT2AMEN1PBRM1POLBNPSR1
SCHEMBL6324478 0.71 MAOA (0.59) KMT2APBRM1POLBTSHRALDH1A1
SCHEMBL8940246 0.71 PBRM1 (0.56) KMT2AMEN1PBRM1POLBNPSR1
SCHEMBL9509046 0.70 TSHR (0.73) KMT2AMEN1POLBADRA2CTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6699830-B1 CROSSLINKED PRODUCT OF COPOLYMER COMPRISING POLYMERIZED UNITS OF UNSATURATED MONOCARBOXYLIC ACID MONOMER AND QUINONE; ABSORBENT RESIN IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-03-02 US disclosed
EP-1086959-A1 CROSSLINKED COPOLYMER OF UNSATURATED CARBOXYLIC ACID AND PROCESS FOR PRODUCING THE SAME, COPOLYMER OF UNSATURATED CARBOXYLIC ACID, BIODEGRADABLE BUILDER, AND DETERGENT COMPOSITION IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-03-28 EP disclosed