SCHEMBL8940246

SCHEMBL8940246

Nc1cccc(C(=O)N(c2ccccc2)c2cccc(N(C(=O)c3cccc(N)c3)c3ccccc3)c2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.56
ESR1 P03372 2/20 0.46
ESR2 Q92731 2/20 0.46
NR3C2 P08235 1/20 0.43
NPSR1 Q6W5P4 2/20 0.42
KMT2A Q03164 4/20 0.42
MEN1 O00255 3/20 0.42
RAB9A P51151 2/20 0.42
GAA P10253 2/20 0.42
NPC1 O15118 1/20 0.41
MITF O75030 1/20 0.41
LMNA P02545 1/20 0.41
POLB P06746 1/20 0.41
F2 P00734 1/20 0.41
PLG P00747 1/20 0.41
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
L3MBTL1 Q9Y468 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2129928 0.95 PBRM1 (0.58) PBRM1ESR1ESR2NR3C2NPSR1
SCHEMBL9001691 0.84 ESR1 (0.54) ESR1ESR2NR3C2NPSR1KMT2A
SCHEMBL15347816 0.82 PARP1 (0.44) PBRM1ESR1ESR2KMT2AMEN1
SCHEMBL30505611 0.82 PARP1 (0.44) PBRM1ESR1ESR2KMT2AMEN1
SCHEMBL6324478 0.80 MAOA (0.59) PBRM1KMT2ARAB9ANPC1POLB
SCHEMBL23877940 0.79 PARP1 (0.52) ESR1ESR2NR3C2NPSR1KMT2A
SCHEMBL27363399 0.79 NR3C2 (0.55) ESR1ESR2NR3C2NPSR1KMT2A
SCHEMBL23924224 0.79 PBRM1 (0.48) PBRM1NPSR1KMT2AMEN1RAB9A
SCHEMBL9358698 0.79 PBRM1 (0.54) PBRM1NPSR1KMT2AMEN1RAB9A
SCHEMBL1003807 0.78 NPSR1 (0.61) ESR1ESR2NR3C2NPSR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0703819-A4 COMPOSITE GAS SEPARATION MEMBRANES AND MAKING THEREOF UOP INC (US) 1996-10-02 EP claimed
EP-0703819-A1 METHOD OF MAKING COMPOSITE GAS SEPARATION MEMBRANES UOP (US) 1996-04-03 EP claimed
WO-1994029002-A1 COMPOSITE GAS SEPARATION MEMBRANES AND MAKING THEREOF UOP (US) 1994-12-22 WO claimed