Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.38 |
| ▸ | DHPS | P49366 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL347520 | 0.81 | BRD4 (0.47) | BRD4HDAC6 | |
| SCHEMBL29430467 | 0.81 | BRD4 (0.47) | BRD4HDAC6 | |
| SCHEMBL15329367 | 0.79 | CYP1A2 (0.46) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28114790 | 0.72 | PDGFRB (0.65) | KDM4EALDH1A1SMN1; SMN2PDGFRBPDGFRA | |
| SCHEMBL30055885 | 0.70 | BRD4 (0.56) | KDM4EBRD4PDE3BPDE3AHDAC6 | |
| SCHEMBL144139 | 0.70 | BRD4 (0.56) | KDM4EBRD4PDE3BPDE3AHDAC6 | |
| SCHEMBL28059287 | 0.70 | HDAC6 (0.42) | BRD4HDAC6 | |
| SCHEMBL28115284 | 0.70 | ALDH1A1 (0.51) | KDM4EALDH1A1SMN1; SMN2PDGFRBPDGFRA | |
| SCHEMBL3873292 | 0.68 | ALDH1A1 (0.49) | KDM4EALDH1A1SMN1; SMN2PDGFRBPDGFRA | |
| SCHEMBL28114789 | 0.68 | ALDH1A1 (0.49) | KDM4EALDH1A1SMN1; SMN2PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421533-A1 | NOVEL ANTI-INFLAMMATORY AGENTS | RESVERLOGIX CORP. (CA) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010123975-A1 | NOVEL ANTI-INFLAMMATORY AGENTS | RESVERLOGIX CORP. (CA) | 2010-10-28 | — | — | WO | disclosed |