Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 4/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | GRM6 | O15303 | 1/20 | 0.30 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6912130 | 1.00 | TAS1R3 (0.35) | TAS1R3TAS1R1TAS1R2GRM2GRM3 | |
| SCHEMBL6916637 | 0.91 | GRM2 (0.47) | GRM2GRM3MEN1ALDH1A1TSHR | |
| SCHEMBL6916632 | 0.91 | GRM2 (0.47) | GRM2GRM3MEN1ALDH1A1TSHR | |
| SCHEMBL6906608 | 0.91 | GRM2 (0.43) | GRM2GRM3TSHRDPP8DPP9 | |
| SCHEMBL6906612 | 0.91 | GRM2 (0.43) | GRM2GRM3TSHRDPP8DPP9 | |
| SCHEMBL6909803 | 0.90 | GRM2 (0.36) | TAS1R3TAS1R1TAS1R2GRM2GRM3 | |
| SCHEMBL6909800 | 0.90 | GRM2 (0.36) | TAS1R3TAS1R1TAS1R2GRM2GRM3 | |
| SCHEMBL6913681 | 0.87 | GRM2 (0.37) | TAS1R3TAS1R1GRM2GRM3MEN1 | |
| SCHEMBL6913679 | 0.87 | GRM2 (0.37) | TAS1R3TAS1R1GRM2GRM3MEN1 | |
| SCHEMBL6911124 | 0.86 | GRM2 (0.38) | TAS1R3TAS1R1GRM2GRM3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116489-A1 | Synthetic excitatory amino acids | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | disclosed |