Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15384472 | 0.89 | — | — | |
| Propane SCHEMBL29024978 | 0.84 | ALDH1A1 (0.78) | TDP1TSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL7934865 | 0.83 | LTA4H (0.56) | TDP1TSHRALDH1A1MAPTNPC1 | |
| Propane SCHEMBL5726617 | 0.74 | MEN1 (0.61) | TDP1TSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL6905981 | 0.74 | KMT2A (0.47) | TDP1TSHRALDH1A1CYP3A4MAPT | |
| Ether SCHEMBL28716761 | 0.73 | ALDH1A1 (0.67) | TDP1TSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL15703 | 0.72 | TDP1 (1.00) | TDP1TSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL11504608 | 0.72 | SMN1; SMN2 (0.50) | ALDH1A1MAPTNPC1RAB9ASMN1; SMN2 | |
| Ethylene Glycol SCHEMBL19307699 | 0.72 | ALDH1A1 (0.74) | TDP1TSHRALDH1A1CYP3A4MAPK1 | |
| SCHEMBL2013073 | 0.72 | ALDH1A1 (1.00) | TDP1TSHRALDH1A1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689899-B2 | HYDROGENATION OF THE CORRESPONDING DINITRO COMPOUNDS | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2004-02-10 | — | — | US | disclosed |
| US-20020019558-A1 | Diamine and acid anhydride | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019558-A1 | Diamine and acid anhydride | CA1, ASIC1, CA4 | TDP1 3268/4885TSHR 3875/4885ALDH1A1 116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.