Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6607690 | 0.79 | CYP4F2 (0.42) | CYP4F2CYP4A11ALDH1A1PKMMMP8 | |
| SCHEMBL1562023 | 0.78 | ALDH1A1 (0.50) | CYP4F2CYP4A11ALDH1A1PKMMMP8 | |
| SCHEMBL27933988 | 0.76 | ALDH1A1 (0.39) | CYP4F2CYP4A11ALDH1A1PKMMMP8 | |
| SCHEMBL8945034 | 0.75 | ALDH1A1 (0.48) | CYP4F2CYP4A11ALDH1A1PKMMMP8 | |
| SCHEMBL8360055 | 0.75 | — | — | |
| SCHEMBL122175 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL5446995 | 0.75 | ALDH1A1 (0.48) | CYP4F2CYP4A11ALDH1A1PKMMMP8 | |
| SCHEMBL8055619 | 0.74 | ALDH1A1 (0.42) | CYP4F2CYP4A11ALDH1A1PKMLMNA | |
| Butane SCHEMBL11358505 | 0.73 | ALDH1A1 (0.46) | CYP4F2CYP4A11ALDH1A1PKMMMP8 | |
| SCHEMBL2036323 | 0.72 | ALDH1A1 (0.50) | CYP4F2CYP4A11ALDH1A1PKMMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427435-A1 | METHOD FOR RE-SENSITIZING VANCOMYCIN RESISTANT BACTERIA USING AGENTS WHICH SELECTIVELY CLEAVE A CELL WALL DEPSIPEPTIDE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003035098-A1 | METHOD FOR RE-SENSITIZING VANCOMYCIN RESISTANT BACTERIA USING AGENTS WHICH SELECTIVELY CLEAVE A CELL WALL DEPSIPEPTIDE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY O F NEW YORK (US) | 2003-05-01 | — | — | WO | disclosed |