Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6912815 | 0.79 | CYP4F2 (0.41) | CYP4F2CYP4A11ALDH1A1PKMLMNA | |
| SCHEMBL10011475 | 0.77 | CYP4F2 (0.43) | CYP4F2CYP4A11ALDH1A1PKMLMNA | |
| SCHEMBL29095033 | 0.77 | DGAT1 (0.42) | ALDH1A1 | |
| SCHEMBL8055619 | 0.76 | ALDH1A1 (0.42) | CYP4F2CYP4A11ALDH1A1PKMLMNA | |
| SCHEMBL27963882 | 0.75 | — | — | |
| SCHEMBL1562023 | 0.74 | ALDH1A1 (0.50) | CYP4F2CYP4A11ALDH1A1PKMLMNA | |
| SCHEMBL1785998 | 0.74 | ALDH1A1 (0.50) | CYP4F2CYP4A11ALDH1A1PKMLMNA | |
| SCHEMBL2036323 | 0.74 | ALDH1A1 (0.50) | CYP4F2CYP4A11ALDH1A1PKMLMNA | |
| SCHEMBL126096 | 0.74 | — | — | |
| SCHEMBL6738960 | 0.73 | MMP8 (0.46) | CYP4F2CYP4A11ALDH1A1PKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1424336-A1 | 1,3-BENZOTHIAZINONE DERIVATIVES AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2004-06-02 | — | — | EP | disclosed |