SCHEMBL6912836

SCHEMBL6912836

COc1ccc(S(=O)(=O)NC(C(N)=O)C(C)c2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.53
MMP9 P14780 5/20 0.52
MMP2 P08253 5/20 0.52
MMP13 P45452 3/20 0.52
MMP1 P03956 2/20 0.52
MMP3 P08254 2/20 0.52
MMP7 P09237 2/20 0.52
POLB P06746 3/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
HTT P42858 1/20 0.52
SLC1A3 P43003 2/20 0.51
SLC1A2 P43004 2/20 0.51
SLC1A1 P43005 2/20 0.51
MMP8 P22894 1/20 0.50
LMNA P02545 4/20 0.48
KMT2A Q03164 2/20 0.48
MEN1 O00255 1/20 0.48
ALDH1A1 P00352 1/20 0.46
ADAMTS4 O75173 1/20 0.44
CA12 O43570 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6925847 0.87 MMP2 (0.58) GAAMMP9MMP2MMP13MMP1
SCHEMBL25185020 0.81 CNR1 (0.57) GAAMMP2POLBSMN1; SMN2HTT
SCHEMBL25185018 0.81 CNR1 (0.57) GAAMMP2POLBSMN1; SMN2HTT
SCHEMBL31477053 0.76 MMP9 (0.69) MMP9MMP2MMP13MMP1MMP3
SCHEMBL29168811 0.75 GAA (0.52) GAAMMP9MMP2MMP13MMP1
SCHEMBL1309027 0.73 GAA (0.50) GAASMN1; SMN2HTTLMNAKMT2A
SCHEMBL25955571 0.73 GAA (0.51) GAAMMP13POLBLMNAKMT2A
Carbamic Acid SCHEMBL30763479 0.72 APP (0.58) GAAPOLBSMN1; SMN2HTTLMNA
SCHEMBL10924203 0.72 PKM (0.70) GAAPOLBLMNAKMT2AMEN1
SCHEMBL3617858 0.72 MMP2 (0.77) MMP9MMP2MMP13MMP1MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004074238-A1 PHENETHYLAMINO SULFAMIC ACIDS THE PROCTER & GAMBLE COMPANY (US) 2004-09-02 WO disclosed
US-20040167183-A1 Phenethylamino sulfamic acids THE PROCTER & GAMBLE COMPANY 2004-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040167183-A1 Phenethylamino sulfamic acids PTPRM, PTPRS, PTPRE GAA 152/4885MMP9 2969/4885MMP2 630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.