Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17550632 | 0.82 | MAPT (0.48) | MAPK1CES1POLBALDH1A1MAPT | |
| SCHEMBL23732969 | 0.80 | MAPT (0.49) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2303355 | 0.78 | MAPT (0.48) | MAPK1CES1CA1CA2ACHE | |
| SCHEMBL254515 | 0.78 | ALDH1A1 (0.37) | MAPK1CES1TDP1POLBGSK3B | |
| SCHEMBL7382446 | 0.78 | CA2 (0.36) | CA1CA2ALDH1A1TSHRMAPT | |
| SCHEMBL19381979 | 0.76 | MAPK1 (0.46) | MAPK1CES1CA1CA2TDP1 | |
| SCHEMBL3581283 | 0.75 | TSHR (0.52) | MAPK1CES1CA1CA2TDP1 | |
| SCHEMBL9163773 | 0.74 | LOXL2 (0.44) | CES1CA1CA2TDP1POLB | |
| SCHEMBL8779823 | 0.74 | LOXL2 (0.44) | CES1CA1CA2TDP1ACHE | |
| SCHEMBL7376074 | 0.74 | CA1 (0.43) | MAPK1CES1CA1CA2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727294-B2 | RADIATION TRANSPARENT MOLDING MATERIALS | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2004-04-27 | — | — | US | disclosed |
| US-20010034419-A1 | Radiation transparent molding materials | MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) | 2001-10-25 | — | — | US | disclosed |