Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18094957 | 0.83 | DPP4 (0.42) | LMNAGAAKMT2ATSHRDPP4 | |
| SCHEMBL1957643 | 0.79 | NFE2L2 (0.43) | LMNAKMT2AL3MBTL1SLC6A4SLC6A2 | |
| SCHEMBL1459660 | 0.78 | ERN1 (0.40) | GAAKMT2ATDP1HTT | |
| SCHEMBL1466243 | 0.78 | CTNNB1 (0.50) | LMNAGAAKMT2ATSHRL3MBTL1 | |
| SCHEMBL1764909 | 0.76 | LMNA (0.55) | LMNAGAAKMT2ATSHRL3MBTL1 | |
| SCHEMBL6908530 | 0.75 | LMNA (0.42) | LMNAGAAKMT2ATSHRSLC6A4 | |
| SCHEMBL7198129 | 0.75 | HTR1A (0.41) | LMNAGAAKMT2ATSHRL3MBTL1 | |
| SCHEMBL872937 | 0.75 | HRH1 (0.55) | LMNAGAAKMT2ATSHRSLC6A4 | |
| SCHEMBL16148965 | 0.75 | KMT2A (0.46) | LMNAGAAKMT2ATSHRL3MBTL1 | |
| SCHEMBL6913020 | 0.74 | SLC6A4 (0.49) | LMNAGAAKMT2ATSHRSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770463-B2 | INSECTICIDES AND ACARICIDES; AROMATIC SUBSTITUTED HALOALKENES | BASF AKTIENGESELLSCHAFT (DE) | 2004-08-03 | — | — | US | disclosed |