Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.72 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE1A | P54750 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081890 | 0.93 | ALOX5 (0.62) | ALOX5PDCD1CD274KDM4ENPC1 | |
| SCHEMBL8085083 | 0.88 | ALOX5 (0.55) | ALOX5PDE5APDE4APDE1APDE1B | |
| SCHEMBL8080370 | 0.84 | ALOX5 (0.52) | ALOX5PDE5APDE4APDE1APDE1B | |
| SCHEMBL8086618 | 0.84 | ALOX5 (0.52) | ALOX5PDE5APDE4APDE1APDE1B | |
| SCHEMBL2955144 | 0.83 | ALOX5 (0.51) | ALOX5KDM4ENPC1ALDH1A1EDNRB | |
| SCHEMBL2955149 | 0.83 | ALOX5 (0.51) | ALOX5KDM4ENPC1ALDH1A1EDNRB | |
| SCHEMBL2955145 | 0.83 | ALOX5 (0.50) | ALOX5PDE1APDE1BPDE1CKDM4E | |
| SCHEMBL6913771 | 0.81 | ALOX5 (0.48) | ALOX5PDE1APDE1BPDE1CKDM4E | |
| SCHEMBL6914615 | 0.78 | TARBP2 (0.46) | ALOX5CYP3A4CYP2D6KDM4ENPC1 | |
| SCHEMBL8086814 | 0.78 | ALOX5 (0.55) | ALOX5PDCD1CD274KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040044069-A1 | Anti-virus compounds | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044069-A1 | Anti-virus compounds | OXER1, ZC3HAV1, NR1H3 | ALOX5 2040/4885PDE5A 4805/4885PDE4A 4854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.