Barbituric Acid

Barbituric Acid

SCHEMBL691401

CCCC.O=C1CC(=O)NC(O)=N1

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.33
DRD2 P14416 1/20 0.31
DRD1 P21728 1/20 0.31
DRD4 P21917 1/20 0.31
DRD5 P21918 1/20 0.31
DRD3 P35462 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Barbituric Acid SCHEMBL7529989 0.93 ITGB3 (0.32)
Barbituric Acid SCHEMBL45717 0.89
Barbituric Acid SCHEMBL20522064 0.87 SRC (0.32) SRC
Barbituric Acid SCHEMBL8492901 0.78 SRC (0.32) SRC
Barbituric Acid SCHEMBL5179348 0.74
SCHEMBL20207033 0.72 GLA (0.31)
SCHEMBL1319575 0.71 LMNA (0.33)
Barbituric Acid SCHEMBL2453572 0.70 KLKB1 (0.30)
SCHEMBL11416505 0.68 SCD (0.36)
SCHEMBL8686387 0.68 POLB (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170153202-A1 DEVICE AND METHOD FOR SEPARATION AND ANALYSIS OF TRACE AND ULTRA-TRACE IONOGENIC COMPOUNDS BY ISOTACHOPHORESIS AND ZONE ELECTROPHORESIS ON CHIP DOLNIK VLADISLAV (US) 2017-06-01 US claimed
EP-3194971-B1 LIGHT-EMITTING VERSIONS OF THE MONOCLONAL ANTIBODY TO C3D (MAB 3D29) FOR IMAGING UNIV COLORADO REGENTS (US) 2023-01-04 EP disclosed
US-11191851-B2 Anti-C3d antibody conjugates and methods of detecting complement activation MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (US) 2021-12-07 US disclosed
US-20200308295-A1 Anti-C3d antibody conjugates and methods of detecting complement activation UNIVERSITAT DE BARCELONA (ES) 2020-10-01 US disclosed
US-10413620-B2 Light-emitting versions of the monoclonal antibody to C3D (MAB 3D29) for imaging THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2019-09-17 US disclosed
US-20190240355-A9 Light-Emitting Versions of the Monoclonal Antibody to C3D (MAB 3D29) for Imaging THE JOHNS HOPKINS UNIVERSITY 2019-08-08 US disclosed
US-20170290930-A1 Light-Emitting Versions of the Monoclonal Antibody to C3D (MAB 3D29) for Imaging UNIV COLORADO REGENTS (US) 2017-10-12 US disclosed
EP-3194971-A2 LIGHT-EMITTING VERSIONS OF THE MONOCLONAL ANTIBODY TO C3D (MAB 3D29) FOR IMAGING University of Colorado Denver (US) 2017-07-26 EP disclosed
US-20170153202-A1 DEVICE AND METHOD FOR SEPARATION AND ANALYSIS OF TRACE AND ULTRA-TRACE IONOGENIC COMPOUNDS BY ISOTACHOPHORESIS AND ZONE ELECTROPHORESIS ON CHIP DOLNIK VLADISLAV (US) 2017-06-01 US disclosed
WO-2016044300-A2 LIGHT-EMITTING VERSIONS OF THE MONOCLONAL ANTIBODY TO C3D (MAB 3D29) FOR IMAGING UNIVERSITY OF COLORADO DENVER (US) 2016-03-24 WO disclosed
US-20020015701-A1 Process for inhibiting complement activation via the alternative pathway GUPTA-BANSAL REKHA (US) 2002-02-07 US disclosed
US-6333034-B1 Process for inhibiting complement activation via the alternative pathway GLIATECH, INC. 2001-12-25 US disclosed
EP-1007092-A1 A PROCESS FOR INHIBITING COMPLEMENT ACTIVATION VIA THE ALTERNATIVE PATHWAY GLIATECH, INC. (US) 2000-06-14 EP disclosed
WO-1999010009-A1 A PROCESS FOR INHIBITING COMPLEMENT ACTIVATION VIA THE ALTERNATIVE PATHWAY GLIATECH INC. (US) 1999-03-04 WO disclosed
US-5753510-A Calibrator for use in test methods for detecting a defective coagulation factor V BEHRING DIAGNOSTICS GMBH (DE) 1998-05-19 US disclosed
EP-0566289-B1 Analysis of hemoglobin variants by capillary electrophoresis BECKMAN INSTRUMENTS INC (US) 1996-02-07 EP disclosed
US-4820635-A ANTIBODIES; COLORIMETRIC, QUANTITATIVE, DIAGNOSTIC THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1989-04-11 US disclosed
US-4722890-A SENSITIVE ENZYME LINKED IMMUNOSORBENT ASSAY THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1988-02-02 US disclosed
US-4267274-A AND NUTRIENT MEDIUM CONTAINING A CARBON SOURCE, A NITROGEN SOURCE AND MINERAL SALTS GRUPPO LEPETIT S.P.A. (IT) 1981-05-12 US disclosed
US-3936497-A HYDROGENATION OF DINITRO WITH NICKEL CATALYST SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-02-03 US disclosed