Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.38 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3691200 | 0.75 | POLB (0.35) | POLBDNMT1CTDSP1TDP1DYRK3 | |
| SCHEMBL22275697 | 0.72 | POLB (0.46) | POLBDNMT1CTDSP1TDP1ALDH1A1 | |
| SCHEMBL7002158 | 0.71 | POLB (0.45) | POLBDNMT1CTDSP1TDP1ALDH1A1 | |
| SCHEMBL20207033 | 0.68 | GLA (0.31) | — | |
| Barbituric Acid SCHEMBL691401 | 0.68 | SRC (0.33) | — | |
| Thiobarbituric SCHEMBL22275895 | 0.68 | — | — | |
| Barbituric Acid SCHEMBL5179348 | 0.67 | — | — | |
| SCHEMBL11416505 | 0.64 | SCD (0.36) | ALDH1A1 | |
| SCHEMBL1319284 | 0.63 | — | — | |
| Barbituric Acid SCHEMBL7529989 | 0.63 | ITGB3 (0.32) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747496-A | Inhibitors of platelet aggregation | ASTRA PHARMACEUTICALS LIMITED (GB) | 1998-05-05 | — | — | US | disclosed |