Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1135100 | 0.76 | MEN1 (0.31) | GPR3 | |
| Hydrochloric Acid SCHEMBL6917168 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL6916544 | 0.69 | GPR3 (0.40) | GPR3 | |
| Hydrochloric Acid SCHEMBL3942644 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL9079025 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL5078321 | 0.64 | GPR3 (0.30) | GPR3 | |
| Hydrochloric Acid SCHEMBL979995 | 0.64 | GPR3 (0.30) | GPR3 | |
| Hydrochloric Acid SCHEMBL2115064 | 0.64 | GPR3 (0.30) | GPR3 | |
| Hydrochloric Acid SCHEMBL3894869 | 0.63 | — | — | |
| SCHEMBL6244794 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0615981-B1 | Supported catalyst system, its preparation and its use in olefin polymerisation | TARGOR GMBH (DE) | 1998-05-06 | — | — | EP | claimed |
| EP-0610852-B1 | Process for preparing cyclo-olefin polymers | HOECHST AG (DE) | 1997-05-07 | — | — | EP | claimed |
| US-5545829-A | Process for preparing cycloolefin copolymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-08-13 | — | — | US | claimed |
| EP-0927201-B1 | CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM | HYUNDAI PETROCHEMICAL CO LTD (KR) | 2004-04-14 | — | — | EP | disclosed |
| EP-0927201-A1 | CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM | Hyundai Petrochemical Co., Ltd. (KR) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998009996-A1 | CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM | HYUNDAI PETROCHEMICAL CO., LTD. (KR) | 1998-03-12 | — | — | WO | disclosed |
| US-5719095-A | FIXING METALLOCENE CATALYST TO SUPPORT BY CONTACT WITH SUPPORTED COCATALYST IN SUSPENSION WHILE IRRADIATING WITH MICROWAVES | HOECHST AG (DE) | 1998-02-17 | — | — | US | disclosed |
| US-5545829-A | Process for preparing cycloolefin copolymers | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-08-13 | — | — | US | disclosed |