Hydrochloric Acid

Hydrochloric Acid

SCHEMBL1135100

CC(C)[Hf+](C1=CC=CC1)C1c2ccccc2-c2ccccc21.CC(C)[Hf+](C1=CC=CC1)C1c2ccccc2-c2ccccc21.[Cl-].[Cl-]

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC6A3 known ✓ Q01959 1/20 0.31
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31
SLC6A4 P31645 1/20 0.31
GPR3 P46089 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6914367 0.76 GPR3 (0.30) GPR3
Hydrochloric Acid SCHEMBL647071 0.66 GPR3 (0.35) GPR3
Hydrochloric Acid SCHEMBL9165907 0.66 MEN1 (0.33) MEN1POLBKMT2AATMGPR3
SCHEMBL9168451 0.65 MEN1 (0.34) MEN1POLBKMT2AATMSLC6A4
Hydrochloric Acid SCHEMBL6557720 0.65 GPR3 (0.34) MEN1POLBKMT2AATMGPR3
Hydrochloric Acid SCHEMBL9421192 0.65
Hydrochloric Acid SCHEMBL818847 0.64 MEN1 (0.31) MEN1POLBKMT2AATMGPR3
Hydrochloric Acid SCHEMBL819707 0.64 MEN1 (0.31) MEN1POLBKMT2AATMSLC6A4
Hydrochloric Acid SCHEMBL819641 0.64 MEN1 (0.31) MEN1POLBKMT2AATMGPR3
Hydrochloric Acid SCHEMBL272679 0.64 SLC6A4 (0.31) SLC6A4SLC6A3GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0513380-B2 PROCESS FOR PRODUCING OLEFINIC POLYMER IDEMITSU KOSAN CO (JP) 2011-02-23 EP disclosed
EP-0513380-B1 PROCESS FOR PRODUCING OLEFINIC POLYMER IDEMITSU KOSAN CO (JP) 1997-10-01 EP disclosed
US-5369196-A Production process of olefin based polymers IDEMITSU KOSAN CO., LTD. (JP) 1994-11-29 US disclosed
EP-0513380-A1 PROCESS FOR PRODUCING OLEFINIC POLYMER IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-11-19 EP disclosed