Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ACAT2 | Q9BWD1 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7085627 | 0.76 | MAOB (0.40) | MAPTPDE7AKDM4EALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL7661598 | 0.75 | MAOB (0.39) | MAPTPDE7AKDM4EALDH1A1KMT2A | |
| SCHEMBL29468014 | 0.74 | GAA (0.44) | MAPTGAAKDM4EALDH1A1TSHR | |
| SCHEMBL9124282 | 0.73 | MAPT (0.38) | MAPTGAAPDE7AKDM4EKMT2A | |
| SCHEMBL7086741 | 0.73 | PDE7A (0.50) | MAPTGAAPDE7AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7649996 | 0.72 | PDE7A (0.49) | MAPTGAAPDE7AKDM4EALDH1A1 | |
| SCHEMBL20104729 | 0.70 | PDE7A (0.38) | PDE7AACAT2LMNAPOLB | |
| SCHEMBL20104727 | 0.70 | PDE7A (0.38) | PDE7AACAT2LMNAPOLB | |
| SCHEMBL29373570 | 0.70 | ALDH1A1 (0.40) | MAPTGAAPDE7AKDM4EALDH1A1 | |
| SCHEMBL6984818 | 0.70 | ALDH1A1 (0.40) | MAPTGAAPDE7AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004093995-A2 | USE OF ANTIOXIDANTS TO TREAT BONE LOSS DISORDERS | ST GEORGE'S ENTERPRISES LIMITED (GB) | 2004-11-04 | — | — | WO | disclosed |