SCHEMBL6914409

SCHEMBL6914409

Cl[Hf](Cl)(C1c2ccccc2-c2ccccc21)(C1c2ccccc2-c2ccccc21)[SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.32
HTR2A P28223 1/20 0.32
SLC22A2 O15244 1/20 0.30
SLC22A3 O75751 1/20 0.30
MEN1 O00255 1/20 0.30
POLB P06746 1/20 0.30
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6916550 0.76 GPR3 (0.39) GPR3HTR2ASLC22A2SLC22A3MEN1
SCHEMBL9069617 0.74 BCHE (0.32)
SCHEMBL217650 0.73 LMNA (0.30)
SCHEMBL7586202 0.67 ACHE (0.42) GPR3HTR2ASLC22A2SLC22A3MEN1
SCHEMBL9172533 0.65 GPR3 (0.35) GPR3HTR2ASLC22A2SLC22A3MEN1
SCHEMBL6919028 0.65 MEN1 (0.41) GPR3HTR2ASLC22A2SLC22A3MEN1
SCHEMBL23532439 0.64 GPR3 (0.38) GPR3HTR2ASLC22A2SLC22A3MEN1
SCHEMBL6910968 0.64 GPR3 (0.39) GPR3HTR2ASLC22A2SLC22A3MEN1
Hydrochloric Acid SCHEMBL7106228 0.64 GPR3 (0.39) GPR3HTR2ASLC22A2SLC22A3MEN1
SCHEMBL7951666 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0927201-B1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM HYUNDAI PETROCHEMICAL CO LTD (KR) 2004-04-14 EP disclosed
EP-0927201-A1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM Hyundai Petrochemical Co., Ltd. (KR) 1999-07-07 EP disclosed
WO-1998009996-A1 CATALYST SYSTEM FOR (CO)POLYMERIZATION OF OLEFINS AND PROCESS FOR THE PREPARATION OF OLEFIN (CO)POLYMERS USING THE CATALYST SYSTEM HYUNDAI PETROCHEMICAL CO., LTD. (KR) 1998-03-12 WO disclosed