4-Methylbenzoic Acid

4-Methylbenzoic Acid

SCHEMBL6914461

Cc1ccc(C(=O)[O-])cc1.Cc1ccc(C(=O)[O-])cc1.Cc1ccc(C(=O)[O-])cc1.[Al+3]

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
LMNA P02545 2/20 0.59
CES2 O00748 2/20 0.59
CES1 P23141 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.56
CA1 P00915 10/20 0.54
CA2 P00918 10/20 0.54
USP2 O75604 1/20 0.53
PKM P14618 2/20 0.52
HTT P42858 2/20 0.52
ATM Q13315 2/20 0.52
NPSR1 Q6W5P4 2/20 0.52
HPGD P15428 1/20 0.52
NLRP1 Q9C000 1/20 0.52
GAA P10253 1/20 0.52
MEN1 O00255 1/20 0.52
NTSR1 P30989 1/20 0.52
KMT2A Q03164 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
SRD5A2 P31213 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Methylbenzoic Acid SCHEMBL1042424 0.95 CA2 (0.61) ALDH1A1LMNACES2CES1SMN1; SMN2
4-Methylbenzoic Acid SCHEMBL19611797 0.95 ALDH1A1 (0.59) ALDH1A1LMNACES2CES1SMN1; SMN2
4-Methylbenzoic Acid SCHEMBL6914890 0.95 ALDH1A1 (0.59) ALDH1A1LMNACES2CES1SMN1; SMN2
4-Methylbenzoic Acid SCHEMBL6915079 0.95 ALDH1A1 (0.59) ALDH1A1LMNACES2CES1SMN1; SMN2
4-Methylbenzoic Acid SCHEMBL9620426 0.95 ALDH1A1 (0.59) ALDH1A1LMNACES2CES1SMN1; SMN2
4-Methylbenzoic Acid SCHEMBL8463954 0.95 ALDH1A1 (0.59) ALDH1A1LMNACES2CES1SMN1; SMN2
4-Methylbenzoic Acid SCHEMBL2784875 0.95 ALDH1A1 (0.59) ALDH1A1LMNACES2CES1SMN1; SMN2
4-Methylbenzoic Acid SCHEMBL6916670 0.95 ALDH1A1 (0.59) ALDH1A1LMNACES2CES1SMN1; SMN2
4-Methylbenzoic Acid SCHEMBL3174416 0.95 ALDH1A1 (0.59) ALDH1A1LMNACES2CES1SMN1; SMN2
4-Methylbenzoic Acid SCHEMBL6914164 0.95 CA1 (0.61) ALDH1A1LMNACES2CES1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6830704-B2 Contains a Lewis acid metal salt and a compound having clathrating ability. TOAGOSEI CO., LTD. (JP) 2004-12-14 US disclosed
US-20030135016-A1 Contains a Lewis acid metal salt and a compound having clathrating ability. TOAGOSEI CO., LTD. 2003-07-17 US disclosed
US-6547985-B1 Adhesive mixture TOGOSEI CO., LTD. (JP) 2003-04-15 US disclosed