4-Methylbenzoic Acid

4-Methylbenzoic Acid

SCHEMBL2784875

Cc1ccc(C(=O)[O-])cc1.[K+]

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA

The experimentally established mechanism targets of 4-Methylbenzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.59
LMNA P02545 2/20 0.59
CES2 O00748 2/20 0.59
CES1 P23141 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.56
CA1 P00915 10/20 0.54
CA2 P00918 10/20 0.54
USP2 O75604 1/20 0.53
PKM P14618 2/20 0.52
HTT P42858 2/20 0.52
ATM Q13315 2/20 0.52
NPSR1 Q6W5P4 2/20 0.52
HPGD P15428 1/20 0.52
NLRP1 Q9C000 1/20 0.52
GAA P10253 1/20 0.52
MEN1 O00255 1/20 0.52
NTSR1 P30989 1/20 0.52
KMT2A Q03164 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
SRD5A2 P31213 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Methylbenzoic Acid SCHEMBL8463954 0.95 ALDH1A1 (0.59) ALDH1A1LMNACES2CES1SMN1; SMN2
4-Methylbenzoic Acid SCHEMBL6914461 0.95 ALDH1A1 (0.59) ALDH1A1LMNACES2CES1SMN1; SMN2
4-Methylbenzoic Acid SCHEMBL6914164 0.95 CA1 (0.61) ALDH1A1LMNACES2CES1SMN1; SMN2
4-Methylbenzoic Acid SCHEMBL6916670 0.95 ALDH1A1 (0.59) ALDH1A1LMNACES2CES1SMN1; SMN2
4-Methylbenzoic Acid SCHEMBL6914890 0.95 ALDH1A1 (0.59) ALDH1A1LMNACES2CES1SMN1; SMN2
4-Methylbenzoic Acid SCHEMBL19611797 0.95 ALDH1A1 (0.59) ALDH1A1LMNACES2CES1SMN1; SMN2
4-Methylbenzoic Acid SCHEMBL9620426 0.95 ALDH1A1 (0.59) ALDH1A1LMNACES2CES1SMN1; SMN2
4-Methylbenzoic Acid SCHEMBL3174416 0.95 ALDH1A1 (0.59) ALDH1A1LMNACES2CES1SMN1; SMN2
4-Methylbenzoic Acid SCHEMBL6915079 0.95 ALDH1A1 (0.59) ALDH1A1LMNACES2CES1SMN1; SMN2
4-Methylbenzoic Acid SCHEMBL1042424 0.95 CA2 (0.61) ALDH1A1LMNACES2CES1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119842077-A Polyphenylene sulfide resin and preparation method thereof 万华化学集团股份有限公司 2025-04-18 CN claimed
CN-119823382-A Polyarylene sulfide resin and preparation method thereof 万华化学集团股份有限公司 2025-04-15 CN claimed
CN-116096105-A Perovskite solar cell with passivated hole transport interface and preparation method thereof 上海交通大学 2023-05-09 CN claimed
WO-2009130708-A2 PREPARATION OF DULOXETINE AND ITS SALTS SHODHANA LABORATORIES LIMITED (IN) 2009-10-29 WO claimed
EP-4375316-B1 METHOD FOR PRODUCING GLASS FIBER-REINFORCED RECYCLED POLYPHENYLENE SULFIDE RESIN COMPOSITION, AND MOLDED ARTICLE OBTAINED BY MOLDING GLASS FIBER-REINFORCED RECYCLED POLYPHENYLENE SULFIDE RESIN COMPOSITION TORAY INDUSTRIES (JP) 2026-03-11 EP disclosed
CN-120035907-A Polyphenylene sulfide resin composition for battery insulating member and battery insulating member 东丽株式会社 2025-05-23 CN disclosed
US-12291612-B2 Fiber-reinforced resin base material TORAY INDUSTRIES, INC. (JP) 2025-05-06 US disclosed
EP-4253481-B1 POLYPHENYLENE SULFIDE RESIN COMPOSITION AND MOLDED ARTICLE TORAY INDUSTRIES (JP) 2025-04-30 EP disclosed
CN-119842077-A Polyphenylene sulfide resin and preparation method thereof 万华化学集团股份有限公司 2025-04-18 CN disclosed
CN-119823382-A Polyarylene sulfide resin and preparation method thereof 万华化学集团股份有限公司 2025-04-15 CN disclosed
US-12234326-B2 Polyphenylene sulfide resin composition and molded article TORAY INDUSTRIES, INC. (JP) 2025-02-25 US disclosed
US-20240343905-A1 METHOD OF PRODUCING GLASS FIBER-REINFORCED RECYCLED POLYPHENYLENE SULFIDE RESIN COMPOSITION, AND MOLDED ARTICLE OBTAINED BY MOLDING GLASS FIBER-REINFORCED RECYCLED POLYPHENYLENE SULFIDE RESIN COMPOSITION TORAY INDUSTRIES, INC. (JP) 2024-10-17 US disclosed
EP-2218715-A1 PHOTOACID GENERATOR AND PHOTOREACTIVE COMPOSITION Sumitomo Seika Chemicals CO. LTD. (JP) 2010-08-18 EP disclosed
WO-2009130708-A2 PREPARATION OF DULOXETINE AND ITS SALTS SHODHANA LABORATORIES LIMITED (IN) 2009-10-29 WO disclosed
WO-2009130708-A2 PREPARATION OF DULOXETINE AND ITS SALTS SHODHANA LABORATORIES LIMITED (IN) 2009-10-29 WO disclosed
CN-101407510-A Preparation of duloxetine hydrochloride intermediate ZHEJIANG HUAHAI PHARM CO LTD (CN) 2009-04-15 CN disclosed
EP-0953598-B1 METHOD FOR RECRYSTALLIZING DIACETAL IN POLYOLEFIN RESIN NEW JAPAN CHEM CO LTD (JP) 2004-12-08 EP disclosed
US-6313204-B1 HEATING AND MELTING A RESIN FORMULATION COMPRISING POLYOLEFIN RESIN, NUCLEATING AGENT CONTAINING DIACETAL COMPOUND TO GIVE MOLTEN RESIN IN WHICH NUCLEATING AGENT IS UNIFORMLY DISSOLVED; COOLING NEW JAPAN CHEMICAL CO., LTD. (JP) 2001-11-06 US disclosed
EP-0953598-A1 METHOD FOR RECRYSTALLIZING DIACETAL IN POLYOLEFIN RESIN NEW JAPAN CHEMICAL CO.,LTD. (JP) 1999-11-03 EP disclosed
EP-0033906-B1 PROCESS FOR THE PRODUCTION OF AROMATIC SULFIDE/SULFONE POLYMERS PHILLIPS PETROLEUM COMPANY (US) 1985-05-15 EP disclosed