Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | STK33 | Q9BYT3 | 11/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6918323 | 0.90 | STK33 (0.51) | GPR35MEN1KMT2ASTK33POLB | |
| SCHEMBL6713465 | 0.89 | GPR35 (0.43) | GPR35TDP1 | |
| SCHEMBL6712048 | 0.88 | GPR35 (0.39) | GPR35MEN1KMT2ASTK33POLB | |
| SCHEMBL6708888 | 0.88 | KDM4E (0.43) | GPR35MEN1KMT2APOLBTDP1 | |
| SCHEMBL6709175 | 0.88 | STK33 (0.40) | GPR35MEN1KMT2ASTK33POLB | |
| SCHEMBL1307817 | 0.87 | GPR35 (0.61) | GPR35MEN1KMT2ASTK33POLB | |
| SCHEMBL6711741 | 0.87 | HIF1A (0.47) | GPR35MEN1KMT2ASTK33TDP1 | |
| SCHEMBL6707953 | 0.87 | MAP3K5 (0.45) | GPR35POLBTDP1 | |
| SCHEMBL6711486 | 0.86 | NPC1 (0.42) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6708158 | 0.84 | GPR35 (0.38) | GPR35POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |