SCHEMBL691452

SCHEMBL691452

O=[C]c1cc2ccccc2cc1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM4 Q8TD43 1/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
MAPT P10636 2/20 0.41
GAA P10253 2/20 0.41
MITF O75030 1/20 0.41
NCOA1 Q15788 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
NCOA3 Q9Y6Q9 1/20 0.41
DAO P14920 4/20 0.39
HPGD P15428 2/20 0.39
DDO Q99489 2/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
TYR P14679 1/20 0.39
AKR1B1 P15121 1/20 0.39
CYP1A2 P05177 1/20 0.39
ALOX5 P09917 1/20 0.38
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10466274 0.96 TDP1 (0.39) TRPM4MEN1KMT2AMAPTGAA
SCHEMBL11542686 0.83 CA1 (0.46) MEN1KMT2ATDP1HPGDCA1
SCHEMBL4259409 0.81 CYP1A2 (0.45) MEN1KMT2ATDP1CYP1A2NPC1
SCHEMBL1298115 0.79 GRIN2D (0.53) TRPM4MEN1KMT2ACYP1A2KDM4E
SCHEMBL4353382 0.77 CA1 (0.53) TRPM4MEN1KMT2AGAANCOA3
SCHEMBL28653 0.74 TRPM4 (0.57) TRPM4MEN1KMT2AMAPTGAA
SCHEMBL29750056 0.74 TRPM4 (0.57) TRPM4MEN1KMT2AMAPTGAA
SCHEMBL29363675 0.74 TRPM4 (0.57) TRPM4MEN1KMT2AMAPTGAA
SCHEMBL28500521 0.74 CYP1A2 (0.39) TRPM4MEN1KMT2AMAPTGAA
SCHEMBL7378720 0.73 IDO1 (0.45) MEN1KMT2AMAPTGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 695 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109486128-A It is a kind of can laser color label plastic paper 杨定吉甫 2019-03-19 CN claimed
CN-109354855-A It is a kind of can laser color label rigid plastics 杨定吉甫 2019-02-19 CN claimed
US-5620987-A Amino acid derivatives HOFFMANN-LA ROCHE INC. (US) 1997-04-15 US claimed
US-5446161-A Protease inhibitor, viricides HOFFMANN-LA ROCHE INC. (US) 1995-08-29 US claimed
EP-0559756-B1 NONAPEPTIDE BOMBESIN ANTAGONISTS UNIV TULANE (US) 1995-04-05 EP claimed
EP-0346847-B1 Amino acid derivatives HOFFMANN LA ROCHE (CH) 1994-05-11 EP claimed
EP-0559756-A1 NONAPEPTIDE BOMBESIN ANTAGONISTS. UNIV TULANE (US) 1993-09-15 EP claimed
US-5244883-A Treating cancer THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 1993-09-14 US claimed
WO-1992009626-A1 NONAPEPTIDE BOMBESIN ANTAGONISTS THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 1992-06-11 WO claimed
EP-0346847-A2 Amino acid derivatives F. HOFFMANN-LA ROCHE AG (CH) 1989-12-20 EP claimed
US-12043639-B2 Polycationic methyl phospholipids for improved delivery of nucleic acids to eukaryotic cells MOLECULAR TRANSFER, INC. (US) 2024-07-23 US disclosed
EP-4384508-A2 LIPIDS FOR NUCLEIC ACID DELIVERY Life Technologies Corporation (US) 2024-06-19 EP disclosed
WO-2024031051-A1 LIPIDS FOR NUCLEIC ACID DELIVERY Life Technologies Corporation (US) 2024-02-08 WO disclosed
US-20240000966-A1 Lipid Compositions For In Vivo Delivery Life Technologies Corporation 2024-01-04 US disclosed
WO-2024006937-A1 LIPID COMPOSITIONS FOR IN VIVO DELIVERY Life Technologies Corporation (US) 2024-01-04 WO disclosed
EP-0346847-A2 Amino acid derivatives F. HOFFMANN-LA ROCHE AG (CH) 1989-12-20 EP disclosed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US disclosed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP disclosed
US-4652512-A DIAZONIUM COMPOUND KANZAKI PAPER MANUFACTURING COMPANY, LIMITED (JP) 1987-03-24 US disclosed
EP-0084890-A1 Diazotype heat development recording medium Toppan Printing Co., Ltd. (JP) 1983-08-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12043639-B2 Polycationic methyl phospholipids for improved delivery of nucleic acids to eukaryotic cells PHOSPHO1, MBOAT7, PLTP TRPM4 2737/4885MEN1 604/4885KMT2A 489/4885
US-20240000966-A1 Lipid Compositions For In Vivo Delivery CHMP4B, LIPA, CETP TRPM4 4183/4885MEN1 1955/4885KMT2A 3841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.