Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6833304 | 0.72 | AKR1C2 (0.61) | SORT1KDM4EACLYDHODHMEN1 | |
| SCHEMBL6919808 | 0.70 | ALDH1A1 (0.42) | KDM4EGLAGRIN1GRIN2AGRIN2B | |
| SCHEMBL6914879 | 0.69 | MAPT (0.42) | KDM4EGLAMEN1KMT2AMAPT | |
| SCHEMBL6919354 | 0.69 | AKR1C2 (0.62) | KDM4EMEN1KMT2AMAPT | |
| SCHEMBL31266680 | 0.67 | DHODH (0.62) | KDM4EGLADHODHMEN1KMT2A | |
| SCHEMBL6918968 | 0.67 | MEN1 (0.42) | SORT1KDM4EGLADHODHMEN1 | |
| SCHEMBL7067508 | 0.67 | AKR1C3 (0.45) | KDM4EGLAMEN1KMT2AMAPT | |
| SCHEMBL30249448 | 0.66 | ALDH1A1 (0.63) | SORT1KDM4EGLADHODHKMT2A | |
| SCHEMBL18214 | 0.66 | ALDH1A1 (0.63) | SORT1KDM4EGLADHODHKMT2A | |
| SCHEMBL25379770 | 0.66 | DHODH (0.50) | SORT1KDM4EGLADHODHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |