Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7126776 | 0.81 | GPR27 (0.42) | MEN1KMT2AMAPTTP53 | |
| SCHEMBL6818060 | 0.76 | AKR1C2 (0.51) | MEN1KMT2ASORT1KDM4EPOLB | |
| SCHEMBL570621 | 0.71 | ALDH1A1 (0.47) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL6914879 | 0.69 | MAPT (0.42) | MEN1KMT2AHTTRXFP1KDM4E | |
| SCHEMBL25171022 | 0.69 | ALDH1A1 (0.44) | MEN1KMT2AHTTRXFP1KDM4E | |
| SCHEMBL17438051 | 0.69 | PTPN1 (0.42) | MEN1KMT2AHTTRXFP1KDM4E | |
| SCHEMBL6919808 | 0.68 | ALDH1A1 (0.42) | MEN1KMT2AHTTKDM4EPOLB | |
| SCHEMBL6914552 | 0.67 | SORT1 (0.42) | MEN1KMT2ARXFP1SORT1KDM4E | |
| SCHEMBL6818553 | 0.66 | AKR1C2 (0.50) | MEN1KMT2AKDM4EPOLBMAPT | |
| SCHEMBL7129937 | 0.65 | PHGDH (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |