Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | VHL | P40337 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6708872 | 0.91 | GRIK1 (0.39) | GRIK1NSD2HDAC3HDAC1LMNA | |
| SCHEMBL6710423 | 0.89 | ALDH1A1 (0.37) | NSD2HDAC3HDAC1LMNAHPGD | |
| SCHEMBL6711425 | 0.88 | PARP14 (0.40) | GRIK1NSD2MEN1KMT2AMAPT | |
| SCHEMBL6713262 | 0.88 | GRIK1 (0.41) | GRIK1NSD2LMNAHPGDSMN1; SMN2 | |
| SCHEMBL6709911 | 0.88 | HIF1A (0.36) | NSD2HDAC3HDAC1LMNAHPGD | |
| SCHEMBL6707664 | 0.88 | NSD2 (0.41) | GRIK1NSD2HDAC3HDAC1LMNA | |
| SCHEMBL6711931 | 0.88 | L3MBTL1 (0.38) | GRIK1NSD2MEN1KMT2AMAPT | |
| SCHEMBL6710051 | 0.87 | MEN1 (0.40) | GRIK1NSD2HDAC3HDAC1MEN1 | |
| SCHEMBL6710107 | 0.87 | GRIK1 (0.39) | GRIK1NSD2HDAC3HDAC1LMNA | |
| SCHEMBL6711957 | 0.86 | GRIK1 (0.40) | GRIK1NSD2HDAC3HDAC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |