Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6712548 | 0.92 | KMT2A (0.48) | ALDH1A1PLA2G7MEN1KMT2AHDAC3 | |
| SCHEMBL6707838 | 0.91 | CSNK1D (0.44) | ALDH1A1PLA2G7MEN1KMT2AHDAC3 | |
| SCHEMBL6710031 | 0.91 | NSD2 (0.41) | NSD2ALDH1A1NPC1PLA2G7MEN1 | |
| SCHEMBL6709037 | 0.91 | PARP14 (0.42) | ALDH1A1PLA2G7MEN1KMT2AGRIK1 | |
| SCHEMBL6710051 | 0.89 | MEN1 (0.40) | NSD2ALDH1A1MEN1KMT2AHDAC3 | |
| SCHEMBL6708561 | 0.89 | NSD2 (0.39) | NSD2ALDH1A1NPC1PLA2G7MEN1 | |
| SCHEMBL6708826 | 0.89 | PLA2G7 (0.39) | ALDH1A1NPC1PLA2G7MEN1KMT2A | |
| SCHEMBL6711425 | 0.88 | PARP14 (0.40) | NSD2NPC1PLA2G7MEN1KMT2A | |
| SCHEMBL6713262 | 0.88 | GRIK1 (0.41) | NSD2PLA2G7MEN1KMT2AGRIK1 | |
| SCHEMBL6914610 | 0.88 | GRIK1 (0.37) | NSD2NPC1PLA2G7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | NSD2 3824/4885ALDH1A1 123/4885NPC1 3891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.