Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 14/20 | 0.38 |
| ▸ | ELOC | Q15369 | 12/20 | 0.38 |
| ▸ | ELOB | Q15370 | 12/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | F12 | P00748 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6918709 | 0.86 | F2 (0.41) | F2F10F12PRSS1PRSS2 | |
| SCHEMBL6914935 | 0.82 | GPBAR1 (0.34) | — | |
| SCHEMBL6919609 | 0.79 | CFD (0.40) | — | |
| SCHEMBL6078132 | 0.78 | F2 (0.51) | ALDH1A1F2F10F12PRSS1 | |
| SCHEMBL6918706 | 0.72 | GPBAR1 (0.36) | F2F10F12PRSS1PRSS2 | |
| SCHEMBL23810801 | 0.71 | VHL (0.57) | VHLELOCELOB | |
| SCHEMBL23810800 | 0.71 | VHL (0.57) | VHLELOCELOB | |
| SCHEMBL30772103 | 0.71 | VHL (0.51) | VHLELOCELOB | |
| Hydrochloric Acid SCHEMBL6919611 | 0.71 | MASP2 (0.36) | F2 | |
| SCHEMBL24514607 | 0.70 | VHL (0.51) | VHLELOCELOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004032834-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2004-04-22 | — | — | WO | disclosed |