SCHEMBL69151

SCHEMBL69151

CC1(C)c2ccc(B3OC(C)(C)C(C)(C)O3)cc2-c2cc(B3OC(C)(C)C(C)(C)O3)ccc21

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LPL P06858 13/20 0.47
LIPG Q9Y5X9 13/20 0.47
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
CA12 O43570 1/20 0.40
CA3 P07451 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
CA5A P35218 1/20 0.40
CA7 P43166 1/20 0.40
CA14 Q9ULX7 1/20 0.40
CA5B Q9Y2D0 1/20 0.40
F11 P03951 1/20 0.39
ESR2 Q92731 1/20 0.36
IRAK4 Q9NWZ3 1/20 0.36
EGFR P00533 1/20 0.36
P4HB P07237 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29639987 0.92 LPL (0.49) LPLLIPGCA1CA2CA9
SCHEMBL10018883 0.92 LPL (0.49) LPLLIPGCA1CA2CA9
SCHEMBL19636272 0.87 LPL (0.52) LPLLIPGCA1CA2CA9
SCHEMBL806820 0.86 LIPG (0.51) LPLLIPGCA1CA2CA9
SCHEMBL17789548 0.86 LPL (0.44) LPLLIPGCA1CA2CA9
SCHEMBL16435209 0.85 LIPG (0.44) LPLLIPGCA1CA2CA9
SCHEMBL69358 0.85 LIPG (0.47) LPLLIPGCA1CA2CA9
SCHEMBL23349135 0.84 LPL (0.45) LPLLIPGCA1CA2CA9
SCHEMBL21730602 0.83 EGFR (0.40) LPLLIPGCA1CA2CA9
SCHEMBL21693390 0.83 LIPG (0.59) LPLLIPGCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130175519-A1 NEW CONDENSED POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-07-11 US disclosed
US-20130175519-A1 NEW CONDENSED POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-07-11 US disclosed
US-8129899-B1 Azafluorene derivative and organic light-emitting device using the derivative CANON KABUSHIKI KAISHA (JP) 2012-03-06 US disclosed
US-20120049176-A1 AZAFLUORENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE USING THE DERIVATIVE CANON KABUSHIKI KAISHA (JP) 2012-03-01 US disclosed
US-8110685-B2 Efficient, durable electron transport layers; low driving voltage; simple, low cost production CANON KABUSHIKI KAISHA (JP) 2012-02-07 US disclosed
US-8110294-B2 Fluorene compound; steric hindrance CANON KABUSHIKI KAISHA (JP) 2012-02-07 US disclosed
US-20080200736-A1 MATERIAL FOR ORGANIC LIGHT-EMITTING ELEMENT AND ORGANIC LIGHT-EMITTING ELEMENT INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2008-08-21 US disclosed
US-20080154040-A1 AZAFLUORENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE USING THE DERIVATIVE CANON KABUSHIKI KAISHA (JP) 2008-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080200736-A1 MATERIAL FOR ORGANIC LIGHT-EMITTING ELEMENT AND ORGANIC LIGHT-EMITTING ELEMENT INCLUDING THE SAME LEF1, FMNL1, AFF1 LPL 1829/4885LIPG 1955/4885CA1 2384/4885
US-20080154040-A1 AZAFLUORENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE USING THE DERIVATIVE AZI2, CYP1A2, CYP2C19 LPL 2008/4885LIPG 2246/4885CA1 2225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.