Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 2/20 | 0.68 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.53 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | EEF2K | O00418 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RGS12 | O14924 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9227326 | 1.00 | GABBR2 (0.68) | GABBR2GABBR1PTGS1PTGS2TNFRSF1A | |
| SCHEMBL9657108 | 0.85 | GABBR2 (0.72) | GABBR2GABBR1PTGS1PTGS2TNFRSF1A | |
| SCHEMBL225772 | 0.84 | GABBR2 (0.75) | GABBR2GABBR1PTGS1PTGS2TNFRSF1A | |
| SCHEMBL6917701 | 0.84 | GABBR2 (0.70) | GABBR2GABBR1PTGS1PTGS2TNFRSF1A | |
| SCHEMBL6917697 | 0.84 | GABBR2 (0.70) | GABBR2GABBR1PTGS1PTGS2TNFRSF1A | |
| SCHEMBL225771 | 0.84 | GABBR2 (0.75) | GABBR2GABBR1PTGS1PTGS2TNFRSF1A | |
| SCHEMBL10001228 | 0.84 | GABBR2 (0.75) | GABBR2GABBR1PTGS1PTGS2TNFRSF1A | |
| SCHEMBL28993505 | 0.83 | GABBR2 (0.64) | GABBR2GABBR1PTGS1PTGS2TNFRSF1A | |
| SCHEMBL9219345 | 0.82 | GABBR2 (0.63) | GABBR2GABBR1PTGS1PTGS2TNFRSF1A | |
| SCHEMBL9219350 | 0.82 | GABBR2 (0.63) | GABBR2GABBR1PTGS1PTGS2TNFRSF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026245-A2 | SUBSTITUTED PHOSPHONATE COMPOUNDS HAVING BONE ANABOLIC ACTIVITY | ILEX ONCOLOGY RESEARCH, SARL (CH) | 2004-04-01 | — | — | WO | disclosed |
| EP-0638084-A1 | SUBSTITUTED PHOSPHONATES, THE PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1995-02-15 | — | — | EP | disclosed |