Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 2/20 | 0.63 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.63 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | EEF2K | O00418 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219345 | 1.00 | GABBR2 (0.63) | GABBR2GABBR1BACE1TNFRSF1APTGS1 | |
| SCHEMBL4450572 | 0.92 | GABBR2 (0.68) | GABBR2GABBR1BACE1TNFRSF1APTGS1 | |
| SCHEMBL4450576 | 0.92 | GABBR2 (0.68) | GABBR2GABBR1BACE1TNFRSF1APTGS1 | |
| SCHEMBL10031552 | 0.83 | GABBR2 (0.64) | GABBR2GABBR1TNFRSF1APTGS1PTGS2 | |
| SCHEMBL9227326 | 0.82 | GABBR2 (0.68) | GABBR2GABBR1TNFRSF1APTGS1PTGS2 | |
| SCHEMBL6915515 | 0.82 | GABBR2 (0.68) | GABBR2GABBR1TNFRSF1APTGS1PTGS2 | |
| SCHEMBL24510590 | 0.79 | ALOX5 (0.66) | GABBR2GABBR1BACE1PTGS1PTGS2 | |
| SCHEMBL9657108 | 0.79 | GABBR2 (0.72) | GABBR2GABBR1TNFRSF1APTGS1PTGS2 | |
| SCHEMBL11318945 | 0.78 | GABBR2 (0.57) | GABBR2GABBR1TNFRSF1APTGS1PTGS2 | |
| SCHEMBL8567993 | 0.78 | GABBR2 (0.66) | GABBR2GABBR1TNFRSF1APTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0638084-A1 | SUBSTITUTED PHOSPHONATES, THE PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1995-02-15 | — | — | EP | disclosed |