Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4939704 | 0.86 | ALOX15 (0.47) | ALOX15PLA2G4BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL244446 | 0.84 | ALOX15 (0.52) | ALOX15SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL9303147 | 0.83 | ALOX15 (0.50) | ALOX15SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL16383050 | 0.82 | ALOX15 (0.57) | ALOX15MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL1345641 | 0.78 | ALOX15 (0.57) | ALOX15PLA2G4BNPC1RAB9AKMT2A | |
| SCHEMBL6915874 | 0.78 | MAPK1 (0.48) | MAPTMAPK1SMN1; SMN2POLBTSHR | |
| SCHEMBL10894517 | 0.78 | ELANE (0.45) | MAPTMAPK1KMT2AMEN1POLB | |
| SCHEMBL9055584 | 0.76 | CYP2C9 (0.55) | MAPTMAPK1POLBCYP2C9CYP2C19 | |
| SCHEMBL11822210 | 0.76 | PLA2G4B (0.55) | PLA2G4BMAPTMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL464497 | 0.76 | ALOX15 (0.63) | ALOX15PLA2G4BSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10100028-B2 | Synthesis routes for prostaglandins and prostaglandin intermediates using metathesis | PATHEON API SERVICES INC. (US) | 2018-10-16 | — | — | US | disclosed |
| US-20160237056-A1 | NOVEL SYNTHESIS ROUTES FOR PROSTAGLANDINS AND PROSTAGLANDIN INTERMEDIATES USING METATHESIS | PATHEON API SERVICES INC. | 2016-08-18 | — | — | US | disclosed |
| WO-2015048736-A1 | NOVEL SYNTHESIS ROUTES FOR PROSTAGLANDINS AND PROSTAGLANDIN INTERMEDIATES USING METATHESIS | IRIX PHARMACEUTICALS, INC. (US) | 2015-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160237056-A1 | NOVEL SYNTHESIS ROUTES FOR PROSTAGLANDINS AND PROSTAGLANDIN INTERMEDIATES USING METATHESIS | PTGES, PTGIS, PTGES2 | ALOX15 24/4885PLA2G4B 52/4885MAPT 4437/4885 |
| US-10100028-B2 | Synthesis routes for prostaglandins and prostaglandin intermediates using metathesis | PTGES, PTGIS, PTGES2 | ALOX15 25/4885PLA2G4B 58/4885MAPT 4497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.