SCHEMBL6915914

SCHEMBL6915914

CCCOc1cc2c(cc1C1CCCC1/C=C/C(C)=C\C(=O)O)C(C)(C)CCC2(C)C

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
RXRA P19793 20/20 0.61
RARB P10826 9/20 0.61
RARG P13631 8/20 0.61
RXRG P48443 12/20 0.58
RXRB P28702 11/20 0.58
RARA P10276 5/20 0.58
PPARG P37231 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6915917 1.00 RXRA (0.61) RXRARARBRARGRXRGRXRB
SCHEMBL6915924 1.00 RXRA (0.61) RXRARARBRARGRXRGRXRB
SCHEMBL7178687 1.00 RXRA (0.61) RXRARARBRARGRXRGRXRB
SCHEMBL6915920 1.00 RXRA (0.61) RXRARARBRARGRXRGRXRB
SCHEMBL6916842 0.90 RXRA (0.49) RXRARARBRARGRXRGRXRB
SCHEMBL4146810 0.90 RXRA (0.61) RXRARARBRARGRXRGRXRB
SCHEMBL14020532 0.90 RXRA (0.61) RXRARARBRARGRXRGRXRB
SCHEMBL4146808 0.90 RXRA (0.61) RXRARARBRARGRXRGRXRB
SCHEMBL7735872 0.75 RXRA (0.52) RXRARARBRARGRXRGRXRB
SCHEMBL7735871 0.75 RXRA (0.52) RXRARARBRARGRXRGRXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040019072-A1 Dimer-selective RXR modulators and methods for their use CANAN-KOCH STACIE (US) 2004-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040019072-A1 Dimer-selective RXR modulators and methods for their use RXRG, RXRB, RXRA RXRA 3/4885RARB 27/4885RARG 25/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.