Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.69 |
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.69 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.69 |
| ▸ | CFTR | P13569 | 1/20 | 0.61 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20580045 | 0.87 | LMNA (0.59) | LMNAMAPTNPSR1POLBGPR55 | |
| SCHEMBL30772290 | 0.86 | CFTR (0.73) | LMNAMAPTNPSR1POLBGPR55 | |
| SCHEMBL3949342 | 0.86 | CFTR (0.73) | LMNAMAPTNPSR1POLBGPR55 | |
| SCHEMBL7805702 | 0.82 | MAPT (1.00) | LMNAMAPTNPSR1POLBGPR55 | |
| SCHEMBL31376524 | 0.82 | TDP1 (0.62) | LMNAMAPTNPSR1POLBGPR55 | |
| SCHEMBL8156691 | 0.81 | POLB (0.64) | LMNAMAPTNPSR1POLBGPR55 | |
| SCHEMBL17105828 | 0.81 | CFTR (0.61) | LMNAMAPTNPSR1POLBGPR55 | |
| SCHEMBL7515313 | 0.80 | LMNA (0.55) | LMNAMAPTNPSR1POLBGPR55 | |
| SCHEMBL14364370 | 0.80 | MAPT (0.62) | LMNAMAPTNPSR1POLBGPR55 | |
| SCHEMBL11849025 | 0.80 | MAPT (0.51) | LMNAMAPTNPSR1POLBGPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617123-B1 | Contacting sample with mixture of an esterase, a pH indicator dye and a buffer; colorimetric analysis; easy, convenient test strips | SMITH JACK V (US) | 2003-09-09 | — | — | US | claimed |
| US-20040121420-A1 | Method for detection of 4-hydroxybutyric acid and its precursor(s) in fluids | SMITH JACK V (US) | 2004-06-24 | — | — | US | disclosed |
| EP-1400574-A1 | Colour changing paint | Akzo Nobel Decorative Coatings Ltd. (GB) | 2004-03-24 | — | — | EP | disclosed |
| US-6617123-B1 | Contacting sample with mixture of an esterase, a pH indicator dye and a buffer; colorimetric analysis; easy, convenient test strips | SMITH JACK V (US) | 2003-09-09 | — | — | US | disclosed |