SCHEMBL7515313

SCHEMBL7515313

Cc1c(N)ccc(C2(c3ccc(N)c(C)c3C)OC(=O)c3ccccc32)c1C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.55
MAPT P10636 6/20 0.55
POLB P06746 3/20 0.55
NPSR1 Q6W5P4 3/20 0.55
GPR55 Q9Y2T6 2/20 0.55
ALOX12 P18054 1/20 0.55
CFTR P13569 1/20 0.51
GOPC Q9HD26 1/20 0.51
MEN1 O00255 5/20 0.48
KMT2A Q03164 5/20 0.48
TDP1 Q9NUW8 4/20 0.48
HTT P42858 2/20 0.48
FTO Q9C0B1 2/20 0.48
CYP2C19 P33261 2/20 0.48
RECQL P46063 2/20 0.48
BLM P54132 2/20 0.48
PRMT1 Q99873 2/20 0.48
ACE2 Q9BYF1 2/20 0.48
GNG2 P59768 1/20 0.48
GNB1 P62873 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4303931 0.80 ALDH1A1 (0.63) LMNAMAPTPOLBNPSR1GPR55
SCHEMBL50862 0.80 LMNA (0.57) LMNAMAPTPOLBNPSR1GPR55
SCHEMBL8156691 0.80 POLB (0.64) LMNAMAPTPOLBNPSR1GPR55
SCHEMBL6916063 0.80 LMNA (0.69) LMNAMAPTPOLBNPSR1GPR55
SCHEMBL20580045 0.79 LMNA (0.59) LMNAMAPTPOLBNPSR1GPR55
SCHEMBL3949342 0.77 CFTR (0.73) LMNAMAPTPOLBNPSR1GPR55
SCHEMBL30772290 0.77 CFTR (0.73) LMNAMAPTPOLBNPSR1GPR55
SCHEMBL17105828 0.76 CFTR (0.61) LMNAMAPTPOLBNPSR1GPR55
SCHEMBL24602926 0.74 GNG2 (0.61) LMNAMAPTPOLBNPSR1GPR55
SCHEMBL17581024 0.74 MAPT (0.57) LMNAMAPTPOLBNPSR1GPR55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020045548-A1 Heat-sensitive recording sheet SAITO CHEMICALS INSTITUTE CO., LTD. (JP) 2002-04-18 US disclosed