Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL391346 | 0.88 | TDP1 (0.48) | TDP1GAAALDH1A1TSHRNFKB1 | |
| SCHEMBL6916631 | 0.88 | TDP1 (0.58) | TDP1GAAALDH1A1TSHRFFAR4 | |
| SCHEMBL7802422 | 0.88 | TDP1 (0.64) | TDP1GAAALDH1A1TSHRFFAR4 | |
| SCHEMBL2889364 | 0.86 | GAA (0.64) | TDP1GAAALDH1A1TSHRNFKB1 | |
| SCHEMBL3225523 | 0.86 | TSHR (0.51) | TDP1GAAALDH1A1TSHRNFKB1 | |
| SCHEMBL10013500 | 0.85 | TSHR (0.56) | TDP1GAAALDH1A1TSHRNFKB1 | |
| SCHEMBL16954218 | 0.85 | TDP1 (0.61) | TDP1GAAALDH1A1TSHRFFAR4 | |
| SCHEMBL14892610 | 0.85 | FFAR4 (0.59) | TDP1GAAALDH1A1TSHRNFKB1 | |
| SCHEMBL7888553 | 0.82 | L3MBTL1 (0.53) | TDP1ALDH1A1TSHRSLC22A12KMT2A | |
| SCHEMBL6379083 | 0.81 | KDM4E (0.51) | TDP1GAAALDH1A1TSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040249188-A1 | Process for the preparation of 3-ethoxy-4-(alkoxy carbonyl)-phenyl acetic acid. (an intermediate of repaglinide) | DR. REDDY'S LABORATORIES LIMITED | 2004-12-09 | — | — | US | claimed |
| CN-101220007-B | Method for producing repaglinide | Zhejiang nexchem pharmaceutical co ltd | 2010-09-15 | — | — | CN | disclosed |
| CN-101220007-A | Method for producing repaglinide | ZHEJIANG NEXCHEM PHARMACEUTICA (CN) | 2008-07-16 | — | — | CN | disclosed |
| US-20040249188-A1 | Process for the preparation of 3-ethoxy-4-(alkoxy carbonyl)-phenyl acetic acid. (an intermediate of repaglinide) | DR. REDDY'S LABORATORIES LIMITED | 2004-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040249188-A1 | Process for the preparation of 3-ethoxy-4-(alkoxy carbonyl)-phenyl acetic acid. (an intermediate of repaglinide) | ALDH1A1, ADRM1, ALDH7A1 | TDP1 1135/4885GAA 93/4885ALDH1A1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.