Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | MAT2A | P31153 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6817279 | 0.92 | UTS2R (0.42) | UTS2RESR1HTR7MAT2AKDM4E | |
| SCHEMBL6822016 | 0.90 | UTS2R (0.39) | UTS2RESR1HTR7KDM4EALDH1A1 | |
| SCHEMBL6917019 | 0.88 | ESR1 (0.48) | ESR1HTR7MAT2AKDM4EALDH1A1 | |
| SCHEMBL6820218 | 0.87 | UTS2R (0.44) | UTS2RESR1HTR7KDM4EALDH1A1 | |
| SCHEMBL6820268 | 0.86 | UTS2R (0.42) | UTS2RESR1HTR7KDM4EALDH1A1 | |
| SCHEMBL6821103 | 0.80 | ESR1 (0.50) | ESR1ALDH1A1SMN1; SMN2TDP1MAPT | |
| SCHEMBL6817304 | 0.79 | ESR1 (0.43) | ESR1HTR7KDM4ETDP1CYP1A2 | |
| SCHEMBL6824409 | 0.78 | KDM4E (0.40) | HTR7MAT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3555167 | 0.78 | HTR6 (0.48) | HTR7MAT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7154224 | 0.77 | ESR1 (0.37) | ESR1HTR7KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |