Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.51 |
| ▸ | PLA2G2A | P14555 | 9/20 | 0.49 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6821103 | 0.90 | ESR1 (0.50) | ESR1HTR6PLA2G2AKMT2AMAPT | |
| SCHEMBL6917019 | 0.87 | ESR1 (0.48) | ESR1KMT2AMAPT | |
| SCHEMBL6820985 | 0.87 | KMT2A (0.56) | HTR6PLA2G2AKMT2ATSHRMAPK1 | |
| SCHEMBL6820250 | 0.85 | ESR1 (0.47) | ESR1HTR6KMT2AMAPK1MAPT | |
| SCHEMBL6817304 | 0.81 | ESR1 (0.43) | ESR1HTR6 | |
| SCHEMBL3557475 | 0.80 | HTR6 (0.45) | HTR6GRIK2KMT2ATSHRMAPT | |
| SCHEMBL3558463 | 0.78 | HTR6 (0.60) | HTR6 | |
| SCHEMBL6821005 | 0.78 | HTR6 (0.53) | HTR6PLA2G2AKMT2ATSHR | |
| SCHEMBL6821058 | 0.77 | PLA2G2A (0.57) | PLA2G2AGRIK2KMT2ATSHRMAPK1 | |
| SCHEMBL3556528 | 0.77 | HTR6 (0.53) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |