Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6912699 | 0.83 | LMNA (0.43) | CYP3A4LMNAKMT2AMEN1 | |
| SCHEMBL6907408 | 0.79 | ALDH1A1 (0.49) | CYP3A4LMNA | |
| SCHEMBL26624253 | 0.78 | MTNR1A (0.53) | MTNR1AMTNR1B | |
| SCHEMBL6906982 | 0.77 | LMNA (0.44) | CYP3A4LMNAACHEKMT2AMEN1 | |
| SCHEMBL6907387 | 0.76 | LMNA (0.45) | CYP3A4LMNAACHEKMT2AMEN1 | |
| SCHEMBL11242342 | 0.75 | KMT2A (0.56) | CYP3A4LMNAACHEKMT2AMEN1 | |
| SCHEMBL6904457 | 0.74 | LMNA (0.43) | CYP3A4LMNAACHEKMT2AMEN1 | |
| SCHEMBL6909985 | 0.74 | LMNA (0.47) | CYP3A4LMNAACHEMTNR1AMTNR1B | |
| SCHEMBL23060398 | 0.73 | CETP (0.46) | — | |
| SCHEMBL4410973 | 0.73 | LMNA (0.56) | CYP3A4LMNAACHEKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1455734-A1 | COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES | Yu, Ruey J., Dr. (US) | 2004-09-15 | — | — | EP | claimed |
| WO-2003045338-A1 | COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES | YU RUEY J (US) | 2003-06-05 | — | — | WO | claimed |