SCHEMBL6917536

SCHEMBL6917536

Cc1cc(C)cc(OB(Oc2ccc(O)cc2)Oc2ccc(O)cc2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
ACHE P22303 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.39
ESR2 Q92731 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
ESR1 P03372 1/20 0.39
LTA4H P09960 3/20 0.38
KDM4E B2RXH2 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35
THRB P10828 1/20 0.35
NR1H2 P55055 1/20 0.34
BAX Q07812 1/20 0.34
ABL1 P00519 1/20 0.34
ABCB1 P08183 1/20 0.34
BCR P11274 1/20 0.34
APP P05067 1/20 0.34
RAPGEF4 Q8WZA2 1/20 0.34
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2851755 0.82 ESR2 (0.55) ALDH1A1ESR2MEN1KMT2AESR1
SCHEMBL4086871 0.82 ALDH1A1 (0.44) ALDH1A1ACHESMN1; SMN2MEN1KMT2A
SCHEMBL10874484 0.77 ALDH1A1 (0.65) ALDH1A1ACHESMN1; SMN2ESR2MEN1
SCHEMBL6917535 0.74 NPSR1 (0.42) ALDH1A1SMN1; SMN2ESR2MEN1KMT2A
SCHEMBL659460 0.73 ACHE (0.52) ALDH1A1ACHEMEN1KMT2AMAPT
SCHEMBL6914024 0.72 KIF11 (0.42) ESR2MEN1KMT2AESR1
SCHEMBL1173553 0.71 ACHE (0.50) ALDH1A1ACHEMEN1KMT2AMAPT
Hydroquinone SCHEMBL8394908 0.70 ALDH1A1 (0.81) ALDH1A1ACHEESR2MEN1KMT2A
SCHEMBL630367 0.69 ALDH1A1 (0.41) ALDH1A1ACHESMN1; SMN2MEN1KMT2A
SCHEMBL4086875 0.69 ALDH1A1 (0.41) ALDH1A1ACHESMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0971962-B1 CATALYST SYSTEM FOR HIGH YIELD SYNTHESIS OF POLYOLEFINS BP CHEM INT LTD (GB) 2004-02-11 EP disclosed
US-6479599-B1 Catalyst system for high yield synthesis of polyolefins BP CHEMICALS LIMITED (GB) 2002-11-12 US disclosed
EP-0946601-B1 IONIC COMPOUNDS FOR CATALYST COMPONENTS, DISPERSIONS AND SOLID ADDITION POLYMERIZATION CATALYSTS CONTAINING THE SAME DOW GLOBAL TECHNOLOGIES INC (US) 2002-09-25 EP disclosed
US-6166161-A Incorporation of functionalized comonomers in polyolefins THE DOW CHEMICAL COMPANY (US) 2000-12-26 US disclosed
EP-0971962-A1 CATALYST SYSTEM FOR HIGH YIELD SYNTHESIS OF POLYOLEFINS THE DOW CHEMICAL COMPANY (US) 2000-01-19 EP disclosed
EP-0946601-A1 CATALYST COMPONENT DISPERSION COMPRISING AN IONIC COMPOUND AND SOLID ADDITION POLYMERIZATION CATALYSTS CONTAINING THE SAME THE DOW CHEMICAL COMPANY (US) 1999-10-06 EP disclosed
WO-1998045337-A1 CATALYST SYSTEM FOR HIGH YIELD SYNTHESIS OF POLYOLEFINS THE DOW CHEMICAL COMPANY (US) 1998-10-15 WO disclosed
US-5783512-A Catalyst component dispersion comprising an ionic compound and solid addition polymerization catalysts containing the same THE DOW CHEMICAL COMPANY (US) 1998-07-21 US disclosed
WO-1998027119-A1 CATALYST COMPONENT DISPERSION COMPRISING AN IONIC COMPOUND AND SOLID ADDITION POLYMERIZATION CATALYSTS CONTAINING THE SAME THE DOW CHEMICAL COMPANY (US) 1998-06-25 WO disclosed