Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 8/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL691486 | 0.79 | RARB (0.35) | RARBALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL692332 | 0.77 | TSHR (0.44) | SMN1; SMN2NPC1TP53RAB9AALDH1A1 | |
| SCHEMBL691310 | 0.72 | POLB (0.39) | SMN1; SMN2ALDH1A1KDM4ELMNATSHR | |
| SCHEMBL691425 | 0.72 | CA2 (0.38) | MEN1KMT2ACYP1A2 | |
| SCHEMBL200372 | 0.70 | RARB (0.79) | MCL1SMN1; SMN2NPC1TP53RAB9A | |
| SCHEMBL12254177 | 0.69 | HIF1A (0.62) | MCL1SMN1; SMN2NPC1TP53RAB9A | |
| Hydrochloric Acid SCHEMBL11652762 | 0.68 | RARB (0.77) | MCL1SMN1; SMN2NPC1TP53RAB9A | |
| Bicarbonate SCHEMBL27643185 | 0.68 | FFAR1 (0.62) | MCL1SMN1; SMN2RARBALDH1A1MEN1 | |
| SCHEMBL44017 | 0.67 | RARB (0.69) | SMN1; SMN2NPC1TP53RAB9ARARB | |
| SCHEMBL10339235 | 0.67 | SMN1; SMN2 (0.61) | MCL1SMN1; SMN2NPC1TP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421501-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND USE THEREOF | The Procter & Gamble Company (US) | 2012-02-29 | — | — | EP | claimed |
| WO-2010123863-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2010-10-28 | — | — | WO | claimed |
| EP-2421501-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND USE THEREOF | The Procter & Gamble Company (US) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010123863-A2 | KERATIN DYEING COMPOSITIONS COMPRISING A RADICAL SCAVENGER AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2010-10-28 | — | — | WO | disclosed |