SCHEMBL200372

SCHEMBL200372

CCCc1ccc(-c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 6/20 0.79
ALDH1A1 P00352 2/20 0.74
MEN1 O00255 1/20 0.74
RARA P10276 1/20 0.74
MAPT P10636 1/20 0.74
MTOR P42345 1/20 0.74
KMT2A Q03164 1/20 0.74
NPC1 O15118 2/20 0.66
RAB9A P51151 2/20 0.66
SMN1; SMN2 Q16637 2/20 0.66
TP53 P04637 1/20 0.66
MCL1 Q07820 1/20 0.60
RXRA P19793 1/20 0.59
RXRB P28702 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.58
PLK1 P53350 1/20 0.56
THRB P10828 1/20 0.55
BCL2 P10415 1/20 0.54
NFKB1 P19838 1/20 0.53
NFKB2 Q00653 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11652762 0.98 RARB (0.77) RARBALDH1A1MEN1RARAMAPT
SCHEMBL44017 0.94 RARB (0.69) RARBALDH1A1MEN1RARAMAPT
Hydrochloric Acid SCHEMBL6560888 0.92 RARB (0.67) RARBALDH1A1MEN1RARAMAPT
Ammonia Solution, Strong SCHEMBL9652121 0.92 RARB (0.67) RARBALDH1A1MEN1RARAMAPT
Methyl Alcohol SCHEMBL38654374 0.92 RARB (0.67) RARBALDH1A1MEN1RARAMAPT
SCHEMBL7825470 0.89 RARB (1.00) RARBALDH1A1MEN1RARAMAPT
SCHEMBL2355289 0.87 RARB (0.96) RARBALDH1A1MEN1RARAMAPT
SCHEMBL1367039 0.87 RARB (1.00) RARBALDH1A1MEN1RARAMAPT
Terephthalic Acid SCHEMBL10409003 0.86 ESR1 (0.63) RARBALDH1A1MEN1RARAMAPT
SCHEMBL12243316 0.86 ALDH1A1 (0.77) RARBALDH1A1MEN1RARAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4073742-A Cyano-substituted biphenyl compounds and liquid crystalline dielectrics containing the same MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1978-02-14 US claimed
US-20250388766-A1 METAL OXIDE DISPERSON AND METHOD FOR MANUFACTURING METAL OXIDE FILM USING SAME TOKYO OHKA KOGYO CO LTD (JP) 2025-12-25 US disclosed
US-20240389450-A1 LIGHT EMITTING ELEMENT, PRODUCTION METHOD FOR LIGHT EMITTING ELEMENT, DISPLAY DEVICE, AND PRODUCTION METHOD FOR DISPLAY DEVICE Sharp Display Technology Corporation (JP) 2024-11-21 US disclosed
CN-117981493-A Light-emitting element, method for manufacturing light-emitting element, display device, and method for manufacturing display device 夏普显示科技株式会社 2024-05-03 CN disclosed
WO-2023248996-A1 METAL OXIDE DISPERSON AND METHOD FOR MANUFACTURING METAL OXIDE FILM USING SAME 東京応化工業株式会社 2023-12-28 WO disclosed
WO-2023079616-A1 LIGHT EMITTING ELEMENT, PRODUCTION METHOD FOR LIGHT EMITTING ELEMENT, DISPLAY DEVICE, AND PRODUCTION METHOD FOR DISPLAY DEVICE シャープディスプレイテクノロジー株式会社 2023-05-11 WO disclosed
US-11072582-B2 Substituted pyrrolidines as G-protein coupled receptor 43 agonists EPICS THERAPEUTICS (BE) 2021-07-27 US disclosed
US-20200347016-A1 SUBSTITUTED PYRROLIDINES AS G-PROTEIN COUPLED RECEPTOR 43 AGONISTS EPICS THERAPEUTICS (BE) 2020-11-05 US disclosed
US-10781171-B2 Substituted pyrrolidines as G-protein coupled receptor 43 agonists EPICS THERAPEUTICS (BE) 2020-09-22 US disclosed
US-20200148636-A1 PYRROLIDINE OR THIAZOLIDINE CARBOXYLIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS AS AGONISTS OF G-PROTEIN COUPLED RECEPTOR 43 (GPR43) EPICS THERAPEUTICS (BE) 2020-05-14 US disclosed
US-20020055631-A1 N-acylsulfonamide apoptosis promoters ABBOTT LABORATORIES 2002-05-09 US disclosed
WO-2002024636-A2 N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS ABBOTT LABORATORIES (US) 2002-03-28 WO disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed
US-5780471-A Tricyclic benzazepine vasopressin antagonists AMERICAN CYANAMID COMPANY (US) 1998-07-14 US disclosed
WO-1996022292-A1 TRICYCLIC VASOPRESSIN ANTAGONISTS AMERICAN CYANAMID COMPANY (US) 1996-07-25 WO disclosed
US-5521173-A TREATING DISEASES CHARACTERIZED BY EXCESS RENAL REABSORPTION OF WATER AMERICAN HOME PRODUCTS CORPORATION (US) 1996-05-28 US disclosed
US-4136053-A BIPHENYL ESTERS AND LIQUID CRYSTALLINE MIXTURES COMPRISING THEM MERCK PATENT GESELLSCHAFT MIT BESCHANKTER HAFTUNG (DE) 1979-01-23 US disclosed
US-4073742-A Cyano-substituted biphenyl compounds and liquid crystalline dielectrics containing the same MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1978-02-14 US disclosed
US-4065489-A Biphenyl esters and liquid crystalline mixtures comprising them MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10781171-B2 Substituted pyrrolidines as G-protein coupled receptor 43 agonists GPR119, GPR52, GPR88 RARB 1314/4885ALDH1A1 1244/4885MEN1 3871/4885
US-20020055631-A1 N-acylsulfonamide apoptosis promoters BAX, BCLAF1, BCL2 RARB 3133/4885ALDH1A1 2460/4885MEN1 4627/4885
US-20200347016-A1 SUBSTITUTED PYRROLIDINES AS G-PROTEIN COUPLED RECEPTOR 43 AGONISTS GPR119, GPR52, GPR88 RARB 1314/4885ALDH1A1 1244/4885MEN1 3871/4885
US-20200148636-A1 PYRROLIDINE OR THIAZOLIDINE CARBOXYLIC ACID DERIVATIVES, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING METABOLIC DISORDERS AS AGONISTS OF G-PROTEIN COUPLED RECEPTOR 43 (GPR43) GPR119, GPR65, GPR84 RARB 642/4885ALDH1A1 1118/4885MEN1 3717/4885
US-20250388766-A1 METAL OXIDE DISPERSON AND METHOD FOR MANUFACTURING METAL OXIDE FILM USING SAME TPR, TMCO1, CD63 RARB 1245/4885ALDH1A1 2705/4885MEN1 3624/4885
US-11072582-B2 Substituted pyrrolidines as G-protein coupled receptor 43 agonists GPR119, GPR52, GPR88 RARB 1314/4885ALDH1A1 1244/4885MEN1 3871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.