SCHEMBL6917751

SCHEMBL6917751

CC1=Cc2c(-c3ccccc3)cc(C(C)C)cc2C1[Zr](C1C(C)=Cc2c(-c3ccccc3)cc(C(C)C)cc21)[SiH](C)C

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27537504 0.85 METAP2 (0.36) METAP2
SCHEMBL19579722 0.82
SCHEMBL27554429 0.82 METAP2 (0.38) METAP2
SCHEMBL6910727 0.80
SCHEMBL29442977 0.79 BRD4 (0.32)
SCHEMBL215863 0.79 BRD4 (0.32)
SCHEMBL2232311 0.79 GABRA1 (0.31)
SCHEMBL27613266 0.79 METAP2 (0.36) METAP2
Hydrochloric Acid SCHEMBL2232224 0.78 GABRA1 (0.30)
Hydrochloric Acid SCHEMBL819254 0.78 BRD4 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6787618-B1 TRANSPARENT, STIFF MOLDING MATERIALS; IMPACT TOUGHNESS; FOOD PACKAGING BASELL POLYPROPYLEN GMBH (DE) 2004-09-07 US disclosed