Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2331366 | 0.84 | PDPK1 (0.54) | PDPK1CES1MAOAMAPTALDH1A1 | |
| SCHEMBL9926495 | 0.72 | PDPK1 (0.58) | PDPK1CES1MAPTALDH1A1MAPK1 | |
| SCHEMBL31119388 | 0.67 | LRRK2 (0.61) | MAOAMAPTALDH1A1MAPK1MAOB | |
| SCHEMBL130358 | 0.67 | LRRK2 (0.61) | MAOAMAPTALDH1A1MAPK1MAOB | |
| SCHEMBL24317500 | 0.67 | CDK2 (0.44) | PDPK1CES1MAPTALDH1A1ALOX15 | |
| SCHEMBL5728638 | 0.66 | PDPK1 (1.00) | PDPK1KDRAURKAAURKBPDGFRA | |
| SCHEMBL5728634 | 0.66 | PDPK1 (1.00) | PDPK1KDRAURKAAURKBPDGFRA | |
| SCHEMBL29779636 | 0.65 | MAOA (0.56) | MAOAMAPTALDH1A1ALOX15HSD17B10 | |
| SCHEMBL51539 | 0.65 | MAOA (0.56) | MAOAMAPTALDH1A1ALOX15HSD17B10 | |
| SCHEMBL9462895 | 0.64 | MAOA (0.54) | MAOAMAPTALDH1A1ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014854-A1 | 3-IMINO-2-INDOLONES FOR THE TREATMENT OF DEPRESSION AND/OR ANXIETY | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2004-02-19 | — | — | WO | disclosed |