Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.61 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.61 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.61 |
| ▸ | FER | P16591 | 1/20 | 0.61 |
| ▸ | LTK | P29376 | 1/20 | 0.61 |
| ▸ | CDK8 | P49336 | 1/20 | 0.61 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31119388 | 1.00 | LRRK2 (0.61) | LRRK2ACVR1MAOAMAOBPDGFRA | |
| SCHEMBL15721488 | 0.81 | LRRK2 (0.50) | LRRK2ACVR1MAOAMAOBPDGFRA | |
| SCHEMBL2420711 | 0.80 | LRRK2 (0.90) | LRRK2ACVR1MAOAMAOBPDGFRA | |
| SCHEMBL366728 | 0.80 | — | — | |
| Isoindigo SCHEMBL9899740 | 0.76 | LRRK2 (0.67) | LRRK2ACVR1MAOAMAOBPDGFRA | |
| Isoindigo SCHEMBL9899736 | 0.76 | LRRK2 (0.67) | LRRK2ACVR1MAOAMAOBPDGFRA | |
| Isoindigo SCHEMBL12386233 | 0.76 | LRRK2 (0.67) | LRRK2ACVR1MAOAMAOBPDGFRA | |
| Isatin SCHEMBL973760 | 0.76 | MAOA (1.00) | LRRK2ACVR1MAOAMAOBPDGFRA | |
| Isatin SCHEMBL34016 | 0.76 | MAOA (1.00) | LRRK2ACVR1MAOAMAOBPDGFRA | |
| SCHEMBL1368292 | 0.76 | LRRK2 (1.00) | LRRK2ACVR1MAOAMAOBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114671880-B | Synthesis and application of indole-2, 3-dinitrile antitumor compounds containing fatty amino | 大连理工大学 | 2023-06-06 | — | — | CN | claimed |
| CN-114671880-A | Synthesis and application of indole-2, 3-dinitrile antitumor compound containing aliphatic amino | 大连理工大学 | 2022-06-28 | — | — | CN | claimed |
| EP-1551396-A1 | PIN1-MODULATING COMPOUNDS AND METHODS OF USE THEREOF | Pintex Pharmaceuticals, Inc. (US) | 2005-07-13 | — | — | EP | claimed |
| WO-2004093803-A2 | PHOTOCHEMOTHERAPEUTIC COMPOUNDS FOR USE IN TREATMENT OF PIN1-ASSOCIATED STATES | PINTEX PHARMACEUTICALS, INC. (US) | 2004-11-04 | — | — | WO | claimed |
| US-20040214872-A1 | Pin1-modulating compounds and methods of use thereof | PINTEX PHARMACEUTICALS, INC. | 2004-10-28 | — | — | US | claimed |
| WO-2004028535-A1 | PIN1-MODULATING COMPOUNDS AND METHODS OF USE THEREOF | PINTEX PHARMACEUTICALS, INC. (US) | 2004-04-08 | — | — | WO | claimed |
| US-11826742-B1 | Effective heterogeneous catalyst of ZnO—TiO2 coated by copper (II) bis-Schiff base hydrazone complex for the organic oxidation processes | King Faisal University (SA) | 2023-11-28 | — | — | US | disclosed |
| US-20130189314-A1 | ENTERIC-COATED HT-2157 COMPOSITIONS AND METHODS OF THEIR USE | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2013-07-25 | — | — | US | disclosed |
| WO-2013109316-A1 | ENTERIC-COATED HT-2157 COMPOSITIONS AND METHODS OF THEIR USE | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2013-07-25 | — | — | WO | disclosed |
| EP-1674526-B9 | POLYACETAL RESIN COMPOSITION | POLYPLASTICS CO (JP) | 2013-05-29 | — | — | EP | disclosed |
| EP-1674526-B1 | POLYACETAL RESIN COMPOSITION | POLYPLASTICS CO (JP) | 2012-12-05 | — | — | EP | disclosed |
| EP-1679346-B1 | POLYACETAL RESIN COMPOSITION | POLYPLASTICS CO (JP) | 2012-11-14 | — | — | EP | disclosed |
| EP-1486536-B2 | FLAME-RETARDANT RESIN COMPOSITION | POLYPLASTICS CO (JP) | 2012-10-10 | — | — | EP | disclosed |
| WO-2004093803-A2 | PHOTOCHEMOTHERAPEUTIC COMPOUNDS FOR USE IN TREATMENT OF PIN1-ASSOCIATED STATES | PINTEX PHARMACEUTICALS, INC. (US) | 2004-11-04 | — | — | WO | disclosed |
| US-20040214872-A1 | Pin1-modulating compounds and methods of use thereof | PINTEX PHARMACEUTICALS, INC. | 2004-10-28 | — | — | US | disclosed |
| EP-1466946-A1 | FLAME-RETARDANT RESIN COMPOSITION | Polyplastics Co., Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |
| EP-1452567-A1 | FLAME-RETARDANT RESIN COMPOSITION | Polyplastics Co Ltd (JP) | 2004-09-01 | — | — | EP | disclosed |
| US-20040082615-A1 | 3-Imino-2-indolones for the treatement of depression and/or anxiety | H. LUNDBECK A/S (DK) | 2004-04-29 | — | — | US | disclosed |
| WO-2004028535-A1 | PIN1-MODULATING COMPOUNDS AND METHODS OF USE THEREOF | PINTEX PHARMACEUTICALS, INC. (US) | 2004-04-08 | — | — | WO | disclosed |
| EP-0847749-B1 | Use of diiminoisoindoline or 3-aminoisoindolone derivatives for the dyeing of keratinic fibers and compositions containing them | OREAL (FR) | 1999-12-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214872-A1 | Pin1-modulating compounds and methods of use thereof | PIN1, FKBP14, PIN4 | LRRK2 1047/4885ACVR1 4665/4885MAOA 4455/4885 |
| US-20040082615-A1 | 3-Imino-2-indolones for the treatement of depression and/or anxiety | GALR3, GALR2, GALR1 | LRRK2 675/4885ACVR1 508/4885MAOA 487/4885 |
| US-20130189314-A1 | ENTERIC-COATED HT-2157 COMPOSITIONS AND METHODS OF THEIR USE | HTR7, HTR5A, HNMT | LRRK2 2189/4885ACVR1 3630/4885MAOA 91/4885 |
| US-11826742-B1 | Effective heterogeneous catalyst of ZnO—TiO2 coated by copper (II) bis-Schiff base hydrazone complex for the organic oxidation processes | CUL2, SOD1, AOC2 | LRRK2 3353/4885ACVR1 4314/4885MAOA 194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.